Search results: protein

Grand Designs at the molecular scale: building custom protein crystals

Grand Designs at the molecular scale: building custom protein crystals

BiochemistryBiotechnologyChemistryMaterials

By Invited Researcher

Order on a molecular scale is difficult to control. The systems with highest possible order are crystals, formed by long arrays of repeating constituent components in all directions. The most familiar examples of crystals encountered in daily life are table salt and sucrose, the sugar in our kitchens. Every grain of table salt is a […]

Nanoscopic motor proteins in the brain build the physical structures of memory

Nanoscopic motor proteins in the brain build the physical structures of memory

NeurobiologyNeuroscience

By Invited Researcher

Author: Albert HiuKa Fok, Postdoctoral Fellow in Neuroscience, McGill University The puzzle of memory has intrigued philosophers and intellects for a very long time. Plato and Aristotle believed that memory was found only in the realm of the soul and the mind, but there was nothing corporeal or physical about it. Memory is closely tied […]

How certain proteins assemble as soon as they are synthesized

How certain proteins assemble as soon as they are synthesized

BiochemistryMolecular biology

By Mapping Ignorance

Proteins, the pillars of cellular function, often assemble into “complexes” to fulfil their functions. A new study reveals why this assembly often begins during the very process of protein synthesis or “birth.” These early interactions involve proteins whose stability depends on their association. They can be compared to a couple in which each partner supports […]

Machine learning cracked the protein-folding problem and won the 2024 Nobel Prize in chemistry

Machine learning cracked the protein-folding problem and won the 2024 Nobel Prize in chemistry

BiochemistryBiologyChemistryComputer science

By Invited Researcher

Author: Marc Zimmer, Professor of Chemistry, Connecticut College The 2024 Nobel Prize in chemistry recognized Demis Hassabis, John Jumper and David Baker for using machine learning to tackle one of biology’s biggest challenges: predicting the 3D shape of proteins and designing them from scratch. This year’s award stood out because it honored research that originated […]

Could the largest known proteins be synthesized by the smallest bacteria?

Could the largest known proteins be synthesized by the smallest bacteria?

BiologyMicrobiology

By Invited Researcher

Author: Ramón Muñoz-Chápuli has been Professor of Animal Biology in the University of Málaga until his retirement. He has investigated for forty years in the fields of developmental biology and animal evolution. On October 11th, I published an article on Mapping Ignorance about the microbial dark matter, the vast diversity of microorganisms that cannot be […]

Counting single proteins with a superconducting nanowire 

Counting single proteins with a superconducting nanowire 

NanotechnologyQuantum physics

By César Tomé

The detection, identification, and analysis of macromolecules is needed in many areas of life sciences, including protein research, diagnostics, and analytics. Mass spectrometry is often used as a detection system for proteins – a method that typically separates charged particles (ions) according to their mass-to-charge-ratio and measures the intensity of the signals generated by a […]

From protein design to materials design

From protein design to materials design

ChemistryMaterials

By BCMaterials

A key feature that makes natural materials highly sustainable and recyclable is their modularity. Biodegradable materials are such because biological organisms can digest and break their constituting chemicals into simpler building blocks. Often such simpler building blocks are then reused for energy or structural purposes. In other words, nature needs materials that can be broken […]

Proteins can also act as brain messengers

Proteins can also act as brain messengers

Molecular biologyNeuroscience

By Rosa García-Verdugo

Brain cells communicate through neurotransmitters like glutamate or dopamine, the substances we got used to reading about when learning about brain function. However, it seems this is not the only way neurons can communicate. A new study suggests that certain proteins can act as brain messengers in the brain. Previously, only pathological proteins like tau […]