Androgenetic alopecia is characterized by a progressive hair loss. This represents a cosmetic issue, treated with a limited set of pharmacological tools such as minoxidil or finasteride. While these therapies can be effective in some patients, their results are often inconsistent and frequently accompanied by unwanted side effects. This has driven researchers to search for […]
For decades, biology textbooks have repeated the same idea with almost ritual certainty: neural stem cells, the cells that fuel the birth of neurons and glia during development, live exclusively inside the brain and spinal cord. They are the architects of the central nervous system, and nowhere else. It has always seemed like an elegant […]
Author: José R. Pineda got his Ph.D. from University of Barcelona in 2006. Since 2007 he has worked for Institut Curie and The French Alternative Energies and Atomic Energy Commission. Currently he is a researcher of the UPV/EHU. He investigates the role of stem cells in physiologic and pathologic conditions. The research group of Wang […]
Stem cells were the pioneering force behind the new wave of personalized medicine of the last decade, while CRISPR and other gene-editing techniques have come to revolutionize gene therapy and the treatment of genetic diseases. It had to happen that they would eventually join forces. A new study has used gene-edited stem cells to revert […]
For a long time it has been posed that induced pluripotent stem cells or iPSC have a great potential in the treatment of certain health issues, what’s more, attending to the results of a recently published study in the journal PNAS , iPSC can be helpful to revert brain stroke damage in mice. Sara Palma-Tortosa […]
SARS-CoV-2 Author: José R. Pineda got his Ph.D. from University of Barcelona in 2006. Since 2007 he has worked for Institut Curie and The French Alternative Energies and Atomic Energy Commission. Currently he is a researcher of the UPV/EHU. He investigates the role of stem cells in physiologic and pathologic conditions. With 676.609.955 cases registered […]
For decades, Alzheimer’s research has been dominated by a seemingly intuitive idea: the disease is largely explained by the accumulation of abnormal proteins in the brain, primarily beta-amyloid and tau. However, while this view has been useful, it has fallen short in explaining certain fundamental aspects. One of the most striking is that Alzheimer’s affects […]
T-cell acute lymphoblastic leukemia (T-ALL) is characterized by the accumulation of genetic lesions that induce differentiation arrest, survival and aberrant proliferation of immature T-cell progenitors . Although T-ALL prognosis has significantly improved due to intensive chemotherapy, relapses still occur in 20% of pediatric patients and 50% of adult patients, often with a dismal outcome. To […]
Multiple myeloma (MM) is an incurable hematological malignancy characterized by clonal expansion of plasma cells in the bone marrow (BM) . Nearly 90% of myeloma patients suffer from skeletal-related events during the course of the disease that not only affect the quality of life but also their overall survival . Myeloma-associated bone disease (MBD) is […]
Author: Mohamady El-Gaby, Postdoctoral Neuroscientist, University of Oxford For decades, neuroscientists have developed mathematical frameworks to explain how brain activity drives behaviour in predictable, repetitive scenarios, such as while playing a game. These algorithms have not only described brain cell activity with remarkable precision but also helped develop artificial intelligence with superhuman achievements in specific […]