Author archives: Rosa García-Verdugo

Image of Rosa García-Verdugo

Rosa studied Biochemistry at University of Oviedo and, after working for a while in immunology at the Center for Biological Research (CIB) and another brief period of systems biology at the Center for Genomic Regulation (CRG), she eventually got her PhD in systems neurobiology at the Max-Planck-Institute of Neurobiology in Munich. Her research deals with neuronal plasticity in mouse visual cortex and big 2-photon microscopes.

Long-term, low-dose THC can improve cognitive decline in mice

Long-term, low-dose THC can improve cognitive decline in mice

HealthPharmacy

By Rosa García-Verdugo

One of the hallmarks of aging is cognitive decline. New research in mice shows that long-term administration with tetrahydrocannabinol (THC), the primary psicoactive component of marihuana, at low doses can have antiaging-effects, particularly on cognitive decline. The endocannabinoid system (ECS) regulates various bodily and brain functions, including sleep, memory and learning, the immune system and […]

Aborted clinical trials: what genetics has to say

Aborted clinical trials: what genetics has to say

GeneticsMedicinePharmacy

By Rosa García-Verdugo

Many (if not most) clinical trials end up failing, but given the bias towards positive results sometimes the reasons for their not working remain unclear. Luckily, a team at Open Targets and EMBL’s European Bioinformatics Institute (EMBL-EBI) have analysed the reasons for aborted clinical trials mentioned in Clinicaltrials.gov, the open-source register for clinical trials worldwide […]

Sexual differences in pain sensation could be due to differing pain receptors

Sexual differences in pain sensation could be due to differing pain receptors

Neuroscience

By Rosa García-Verdugo

Pain is highly personal. What to some doesn’t even deserve the name, for others can be unbereable. Now, we just discovered a difference in how we feel it: men and women have different pain receptors. Recent research has demonstrated in rodents and, importantly, primates including humans, that there are sex differences in pain receptors, also […]

Stopping jumping genes could increase lifespan, at least in worms

Stopping jumping genes could increase lifespan, at least in worms

Genetics

By Rosa García-Verdugo

Roundworms are the most commonly used animal model to investigate aging and methods to increase the lifespan such as intermittent fasting. Latest research indicates that jumping genes could be another target for interventions aiming towards expanding the lifespan. What are jumping genes? Also called transposons, are movable stretches of DNA of possible viral origin that […]