Category archives: Molecular biology

3 medical innovations fueled by COVID-19 that will outlast the pandemic

3 medical innovations fueled by COVID-19 that will outlast the pandemic

Computer scienceGeneticsHealthMedicineMolecular biologyPharmacy

By Invited Researcher

A number of technologies and tools got a chance to prove themselves for the first time in the context of COVID-19. Three researchers working in gene-based vaccines, wearable diagnostics and drug discovery explain how their work rose to the challenge of the pandemic, and their hopes that each technology is now poised to continue making […]

STOP the STOP in cancer: evading pathogenic premature translation termination of tumor suppressors

STOP the STOP in cancer: evading pathogenic premature translation termination of tumor suppressors

BiomedicineMedicineMolecular biology

By Invited Researcher

Inherited or somatic mutations targeting genes which encode essential cell growth regulatory proteins favor the emergence of cancer. Cells carrying these mutations acquire growing and survival advantages that trigger the emergence of the tumor. A large number of tumor-associated mutations, as well as many mutations found in the germline of hereditary cancer patients, are single-nucleotide […]

Mapping PTEN: basic research to assist precision oncology

Mapping PTEN: basic research to assist precision oncology

BiomedicineMedicineMolecular biology

By Invited Researcher

In the last two decades, the easiness in the obtaining of genetic information from patient biological samples, together with the advanced knowledge on the physiological consequences of patient genetic alterations, has transformed the daily clinical practice in our hospitals. As a result, the current use of the precision medicine concept, as disseminated today in the […]

Molecular mechanisms underlying the link between cannabis abuse and schizophrenia

Molecular mechanisms underlying the link between cannabis abuse and schizophrenia

HealthMolecular biologyPharmacy

By Invited Researcher

Author: Leyre Urigüen is a researcher at the Department of Pharmacology, University of the Basque Country UPV/EHU and Centro de Investigación Biomédica en Red de Salud Mental CIBERSAM Cannabis, also called marijuana, is a drug that comes from the plant Cannabis sativa (hemp plant). The plant contains more than 400 different chemicals, of which approximately […]

A generalized approach for NMR studies of lipid–protein interactions

A generalized approach for NMR studies of lipid–protein interactions

BiochemistryChemistryMolecular biology

By Invited Researcher

Author: Francisco J. Blanco is an Ikerbasque Research Professor at CIC bioGUNE Molecular interactions in cell membranes, particularly lipid-protein interactions in their hydrophobic core, are difficult to analyse and remain poorly characterised despite high relevance in physiological and pathological processes. Structural rearrangements in membranes and embedded proteins, and the way molecular interactions contribute to their […]

MicroRNA-loaded nanoparticles against liver metastasis

MicroRNA-loaded nanoparticles against liver metastasis

BiomedicineMolecular biology

By Invited Researcher

Author: Iker Badiola is an assistant professor in the Department of Cell Biology and Histology, Faculty of Medicine and Nursery, University of Basque Country (UPV/EHU). Colorectal cancer is the third most frequently occurring cancer and a common cause of cancer-related death worldwide. The origin of colorectal cancer is usually a malignant polyp developed in the […]