Category archives: Medicine

How to treat Parkinson’s with astrocytes

How to treat Parkinson’s with astrocytes

MedicineNeuroscience

By Rosa García-Verdugo

Parkinson’s disease is characterized by neuronal loss in the brain’s substantia nigra region. What if another cell type, namely, astrocytes, could replace them? The work of two research groups recently published Zhou, H. et al. Cell 181, 590–603.e16 (2020). shows that, at least in mice, transforming astrocytes (a non-neuronal cell type in the brain) into […]

Health-related quality of life in chronic obstructive pulmonary disease patients

Health-related quality of life in chronic obstructive pulmonary disease patients

MathematicsMedicine

By BCAM

Chronic diseases are already having and will continue to have not only profound economic, social and individual consequences but also a major impact on the use of health resources and design of new care processes. Chronic obstructive pulmonary disease (COPD) is a case on point. COPD is airflow limitation caused by an inflammatory response to […]

Genetic risk for Alzheimer’s also predisposes for COVID-19 infection

Genetic risk for Alzheimer’s also predisposes for COVID-19 infection

BiomedicineGeneticsMedicine

By Rosa García-Verdugo

It seems that the genetic risk of an APOE4 variant in the APOE gene would not only increase risk for Alzheimer’s but also would increase the chances of getting infected by the COVID-19 virus. The APO protein is involved in cholesterol metabolism and the immune system. However, its precise role in Alzheimer’s disease is as […]

Pathogen reduction technologies and the shelf life of platelet concentrates

Pathogen reduction technologies and the shelf life of platelet concentrates

MathematicsMedicine

By Invited Researcher

Author: Mikel Lezaun is professor at the University of the Basque Country – UPV/EHU where he is director of the Mathematical Technology Transfer Group Production centers for blood components have the job of supplying hospitals with the products that they need in time and strive to discard as few units as possible due to outdating […]

Effective mathematical modelling of fractional-diffusion in cardiac electrophysiology

Effective mathematical modelling of fractional-diffusion in cardiac electrophysiology

MathematicsMedicine

By BCAM

The Hodgkin-Huxley model for the generation of the nerve action potential is one of the most successful mathematical models of a complex biological process that has ever been formulated. Alan Hodgkin and Andrew Huxley described the model in 1952 to explain the ionic mechanisms underlying the initiation and propagation of action potentials in the squid […]

Heterogeneous sorroundings are critical in the analysis of nerve ablation for treating chronic pains

Heterogeneous sorroundings are critical in the analysis of nerve ablation for treating chronic pains

Computer scienceMathematicsMedicine

By BCAM

Chronic pain is one of the most common problems of advanced age. Even though the combination of physical therapy and analgesics such as nonsteroidal anti-inflammatory drugs is effective in chronic pain treatments, it only confers short-term benefits. On the other hand, it could be quite expensive and may have significant adverse side effects. Effective, lasting […]

T cells could be key for early Alzheimer’s detection

T cells could be key for early Alzheimer’s detection

BiomedicineMedicineNeurobiology

By Rosa García-Verdugo

For a long time Alzheimer disease has been studied mostly as a neuronal disease. However, recently the role of the immune system is getting more attention and its involvement more clear. Recent research has shown that a subpopulation of T cells could be key to early Alzheimer’s detection. How were these T cells discovered? Firstly […]