Author archives: Rosa García-Verdugo

Image of Rosa García-Verdugo

Rosa studied Biochemistry at University of Oviedo and, after working for a while in immunology at the Center for Biological Research (CIB) and another brief period of systems biology at the Center for Genomic Regulation (CRG), she eventually got her PhD in systems neurobiology at the Max-Planck-Institute of Neurobiology in Munich. Her research deals with neuronal plasticity in mouse visual cortex and big 2-photon microscopes.

How to treat Parkinson’s with astrocytes

How to treat Parkinson’s with astrocytes

MedicineNeuroscience

By Rosa García-Verdugo

Parkinson’s disease is characterized by neuronal loss in the brain’s substantia nigra region. What if another cell type, namely, astrocytes, could replace them? The work of two research groups recently published Zhou, H. et al. Cell 181, 590–603.e16 (2020). shows that, at least in mice, transforming astrocytes (a non-neuronal cell type in the brain) into […]

A common gene variant associated with short height in Peruvians

A common gene variant associated with short height in Peruvians

Biology

By Rosa García-Verdugo

Like intelligence, height is genetically determined, however there are thousands of genes implicated in height determination. That is why the finding by researchers from Harvard Medical School of a gene variant responsible for shortening the average height of Peruvians in about 2.2 centimetres is so interesting. There are other rare gene variants known that cause […]

A microscopy method to look at amyloid protein structure

A microscopy method to look at amyloid protein structure

NeurobiologyNeuroscience

By Rosa García-Verdugo

Amyloid plaques are a hallmark of some neurodegenerative diseases like Alzheimer’s or Parkinson’s. Even though the exact role of amyloid protein in the disease is not clear, being able to follow amyloid protein misfolding and plaque formation could be a step forward for the study of the disease. Now, Matthew Lew’s lab has developed a […]

Genetic risk for Alzheimer’s also predisposes for COVID-19 infection

Genetic risk for Alzheimer’s also predisposes for COVID-19 infection

BiomedicineGeneticsMedicine

By Rosa García-Verdugo

It seems that the genetic risk of an APOE4 variant in the APOE gene would not only increase risk for Alzheimer’s but also would increase the chances of getting infected by the COVID-19 virus. The APO protein is involved in cholesterol metabolism and the immune system. However, its precise role in Alzheimer’s disease is as […]