Category archives: Science

Adipocytes orchestrate T-cell acute lymphoblastic leukemia propagation

Adipocytes orchestrate T-cell acute lymphoblastic leukemia propagation

Biomedicine

By Invited Researcher

T-cell acute lymphoblastic leukemia (T-ALL) is a devastating disease of T-cell progenitors that mainly affects children and young adults. Numerous genomic alterations are known to induce survival, proliferation, and differentiation of T-ALL cells . The interactions between leukemic cells and their microenvironment are known factors that contribute to T-ALL pathogenesis. The bone marrow (BM) microenvironment […]

All-optical nonlinear Compton scattering using a ultrahigh intensity laser pulse

All-optical nonlinear Compton scattering using a ultrahigh intensity laser pulse

AstrophysicsPhysicsQuantum physics

By Mapping Ignorance

A team of researchers has successfully demonstrated nonlinear Compton scattering (NCS) between an ultra-relativistic electron beam and an ultrahigh intensity laser pulse using the 4-Petawatt laser at the Center for Relativistic Laser Science (CoReLS) within the Institute for Basic Science at Gwangju Institute of Science and Technology (GIST), Korea. The innovation is the use of […]

Mechanodrugs

Mechanodrugs

BiochemistryDIPC BiochemistryPharmacy

By DIPC

Numerous proteins in the cell withstand mechanical loads while performing their function. This is especially significant for cell-surface proteins located in the extracellular matrix, which are essential for the communication between cells in the extracellular milieu. Reacting to mechanical force through conformational changes is crucial for these cell-surface proteins, translating a physical signal into an […]

Astrocytes transplantation as a treatment for some neurological disorders

Astrocytes transplantation as a treatment for some neurological disorders

Neuroscience

By Invited Researcher

Authors: Albert HiuKa Fok, Postdoctoral Fellow in Neuroscience, McGill University and Sabrina Chierzi, Research Associate, Neuroscience, McGill University Astrocytes — named for their star-like shape — are a type of brain cell as abundant as neurons in the central nervous system, but little is known about their role in brain health and disease. Many neurological […]

Multiple Denisovan interbreeding events with modern humans

Multiple Denisovan interbreeding events with modern humans

AnthropologyEvolutionGenetics

By Mapping Ignorance

Scientists believe individuals of the most recently discovered hominin group (the Denisovans) that interbred with modern day humans passed on some of their genes via multiple, distinct interbreeding events that helped shape early human history. In 2010, the first draft of the Neanderthal genome was published, and comparisons with modern human genomes revealed that Neanderthal […]