Category archives: Biochemistry

Nanoparticles, those minuscule marvels measured in billionths of a metre, hold immense promise for revolutionizing cancer treatment. Their ability to deliver drugs directly to tumours could transform therapies, but only if they can navigate the dense, complex environment of tumour tissue. A new review , that includes a new experimental data set, explores this challenge […]

The light of someone’s life might not be just another person, but light in the literal sense. According to a recent study , every living system emits light without requiring external excitation due to a biological phenomenon known as ultraweak photon emission (UPE). In mice, UPE was linked to vitality as live mice emitted significantly […]

Imagine peering through a microscope, marvelling at the intricate dance of cells, proteins, or tiny structures within a living organism. These images, known as bioimages, are a treasure trove of information for scientists studying life’s mysteries, from how cells divide to how diseases disrupt tissues. But analysing these images is no small feat. The sheer […]

Life may not have begun with a dramatic lightning strike into the ocean but from many smaller “microlightning” exchanges among water droplets from crashing waterfalls or breaking waves. New research shows that water sprayed into a mixture of gases thought to be present in Earth’s early atmosphere can lead to the formation of organic molecules […]

Proteins, the pillars of cellular function, often assemble into “complexes” to fulfil their functions. A new study reveals why this assembly often begins during the very process of protein synthesis or “birth.” These early interactions involve proteins whose stability depends on their association. They can be compared to a couple in which each partner supports […]

The origins of life on Earth remain one of the most fascinating and profound questions in science. A new research sheds light on this mystery by exploring how the building blocks of life could have formed under early Earth conditions. In this study, we focused on understanding how simple chemicals might have come together to […]

Numerous proteins in the cell withstand mechanical loads while performing their function. This is especially significant for cell-surface proteins located in the extracellular matrix, which are essential for the communication between cells in the extracellular milieu. Reacting to mechanical force through conformational changes is crucial for these cell-surface proteins, translating a physical signal into an […]

Author: Marc Zimmer, Professor of Chemistry, Connecticut College The 2024 Nobel Prize in chemistry recognized Demis Hassabis, John Jumper and David Baker for using machine learning to tackle one of biology’s biggest challenges: predicting the 3D shape of proteins and designing them from scratch. This year’s award stood out because it honored research that originated […]

The protein “MIPS” changes its internal structure when it becomes active. Its disordered active centre becomes a defined structure with special functions. The protein plays a key role in the production of inositol, which is also known as vitamin B8, and fulfils important tasks in the body. A team of researchers has succeeded for the […]

A new imaging technique can give scientists a much closer look at fibril assemblies, stacks of peptides like amyloid beta, most notably associated with Alzheimer’s disease. These cross-β fibril assemblies are also useful building blocks within designer biomaterials for medical applications, but their resemblance to their amyloid beta cousins, whose tangles are a symptom of […]