A new imaging technique can give scientists a much closer look at fibril assemblies, stacks of peptides like amyloid beta, most notably associated with Alzheimer’s disease. These cross-β fibril assemblies are also useful building blocks within designer biomaterials for medical applications, but their resemblance to their amyloid beta cousins, whose tangles are a symptom of […]
Biochemistry • Biomedicine • Health • Medicine • Neuroscience
Recent research has demonstrated that obesity impairs the mechanisms that allow our brains to realize when our stomachs are full and that these changes are maintained despite dieting, giving insights into why it is difficult for obese people to avoid excessive eating and why there is often a yo-yo effect after dieting. It has been […]
Pyrite, also known as “fool’s gold,” is an abundant iron sulphide mineral in the Earth’s crust. All organisms need iron and sulphur to grow. Because pyrite does not dissolve in oxygen-free conditions, scientists previously thought that organisms could not use pyrite in the absence of oxygen. Research shows that certain single-celled microorganisms can dissolve pyrite […]
Plants that inhabit the Earth have the incredible ability to grow continually for hundreds of years, and always towards the light of the sun, which provides them with the necessary energy to sprout. At the source of this growth are changes in their environment, such as variations in light, temperature and humidity. But new stimuli […]
Body odor is present in all mammals, including of course humans. It has a clear genetic basis, although it is modulated by different conditions, both normal and pathological. Interestingly, although it is believed to have an important communicative function and to be involved in sexual attraction, body odor is considered unpleasant by most people, which […]
Dip. Di Chemica, Università di Torino, via P. Giuria 7, 10125, Torino, Italy * adrian.matencioduran@unito.it The last articles of one of us (Matencio) [1,2,3,4] were about the different uses of a complexing agent called cyclodextrin (CD), a torus-shaped oligosaccharide made up of α-(1,4) linked glucose units, the most common CDs being α, β and γ-CD […]
On our unique planet, life evolved under the pressure of natural selection. The evolution theory of Darwin demonstrates the incredible plasticity of the living organism. For millions of years, living organisms explored the conformational universe of proteins introducing new structures and function through genetic mutations. The genetic modifications are translated into the sequence of amino-acids […]
Departamento de Bioquímica y Biología molecular-A, Facultad de Biología, Universidad de Murcia, E-30100 Murcia, Spain * adrian.matencio@um.es Antimicrobial resistance is a problem in our society. Although several authors have focused on seeking new molecules with antimicrobial activity, resistance has increased. Several authors are looking for new antimicrobial substances or seeking to improve the use of […]
Molecular recognition is a critical process for many biological functions and consists in non-covalent binding of different molecules, such as protein-protein, antigen-antibody and many others. The host-guest molecules involved often show a shape complementarity, and one of the leading specification for molecular recognition is that the interaction must be selective, i.e. the host should strongly […]
It is time to round off this trilogy of articles about the importance of basic science nowadays. But first, how does science improve? A research team selects a topic, creates its hypothesis and workflow and, perhaps, tries to publish an article with the findings. This article is read by a new research team, who will […]