Category Archives: Biochemistry
A universal theory for heteropolymer design
Author: Ivan Coluzza is an Ikerbasque Research Professor at CICbiomaGUNE
On our unique planet, life evolved under the pressure of natural selection. The evolution theory of Darwin demonstrates the incredible plasticity of the living organism. For millions of years, living […]
Could excipients decrease antimicrobial properties? Citronellal oil and cyclodextrins
Authors: Adrián Matencio* & Carolina Abril-Sánchez.
Departamento de Bioquímica y Biología molecular-A, Facultad de Biología, Universidad de Murcia, E-30100 Murcia, Spain
* adrian.matencio@um.es
Antimicrobial resistance is a problem in our society. Although several authors have focused on seeking new molecules […]
Design of protein-protein binding sites suggests a rationale for naturally occurring contact areas
Author: Ivan Coluzza is an Ikerbasque Research Professor at CICbiomaGUNE
Molecular recognition is a critical process for many biological functions and consists in non-covalent binding of different molecules, such as protein-protein, antigen-antibody and many others. The host-guest molecules involved often […]
When we forget basic science. Seeking the small details out
Author: Adrián Matencio is pursuing a PhD at the Department of Biochemistry and Molecular Biology – A, Faculty of Biology, University of Murcia, where he graduated in biotechnology.
It is time to round off this trilogy of articles about […]
A generalized approach for NMR studies of lipid–protein interactions
Author: Francisco J. Blanco is an Ikerbasque Research Professor at CIC bioGUNE
Molecular interactions in cell membranes, particularly lipid-protein interactions in their hydrophobic core, are difficult to analyse and remain poorly characterised despite high relevance in physiological and pathological processes. […]
Early research on the origin of life. The Miller experiment.
“It is often said that all the conditions for the first production of a living organism are now present, which could ever have been present.— But if (& oh what a big if) we could conceive in some warm […]
The mechanochemistry of E. coli type 1 pilus
Uropathogenic Escherichia coli (UPEC) is responsible for approximately 90% of urinary tract infections (UTI) seen in individuals with an ordinary anatomy. In ascending infections, fecal bacteria colonize the urethra and spread up the urinary tract to the bladder as […]
A new theory on the early building blocks of life
From nucleic acids to proteins and sugar chains, all life is made up of polymers, large molecules made up of sequences of small units called monomers. However, how these macromolecules first appeared on the surface of Earth is still controversial. […]
When we forget basic science. A jar is not a jug
Author: Adrián Matencio is pursuing a PhD at the Department of Biochemistry and Molecular Biology – A, Faculty of Biology, University of Murcia, where he graduated in biotechnology.
Applicability or some usefulness is the mantra of new I+D research. However, […]
When we forget basic science. An example concerning solubility
Author: Adrián Matencio is pursuing a PhD at the Department of Biochemistry and Molecular Biology – A, Faculty of Biology, University of Murcia, where he graduated in biotechnology.
Nowadays, most important news concerning science focuses on applicability; if […]