Rita Carlos is a Post Doc fellow at the Instituto Gulbenkian Ciência in Portugal. Her main interest is to understand how DNA repair mechanism impact on different diseases. Rita did her PhD at the University of Oxford and this focused on the role of DNA damage responses in maintaining genomic stability and preventing tumorigenesis. Currently she is exploring the impact of the DNA damage response on the pathogenesis of immune-mediated inflammatory diseases.
DNA damage is one of the most deleterious forms of cellular damage. If unrepaired, DNA lesions can create genomic instability, a hallmark of cancer . As most of the DNA is confined to the nucleus, for many years the study of DNA damage response has mainly focused on its nuclear effects, including mechanisms such as […]