Author archives: Rosa García-Verdugo

A blinding mutation that might increase intelligence

A blinding mutation that might increase intelligence

GeneticsNeuroscience

By Rosa García-Verdugo

How to breed more intelligent humans? This is a difficult question, one which raises numerous issues, both ethical and scientific. Would you give your eyesight away to become brighter? As crazy as this question may sound, a blinding mutation might increase intelligence. The CORD7 (cone-rod dystrophy 7) mutation of the RIMS1 gene produces progressive blindness […]

Intermittent fasting could improve nerve regeneration

Intermittent fasting could improve nerve regeneration

Molecular biologyNeuroscience

By Rosa García-Verdugo

Intermittent fasting is more than the latest diet fad, it has proven benefits –at least in animal models– against longevity, and it appears that it could even improve nerve regeneration, according to new research. The problems with axons in the peripheral nervous system is that their regenerative capacity is not very high. There are certain […]

What your eyes can tell

What your eyes can tell

Neuroscience

By Rosa García-Verdugo

A common saying refers to the power of the eyes as a window inside our souls; interestingly, our eyes could also be a window into our brains, helping identify certain neurological conditions like attention deficit hyperactivity disorder (ADHD) or autism spectrum disorder (ASD). Recent work published in Frontiers in Neuroscience found distinct electrical recording signatures […]

Unexpected effects of gene editing: aggressive hamsters

Unexpected effects of gene editing: aggressive hamsters

Genetics

By Rosa García-Verdugo

In the last years, CRISPR-Cas9 technology has revolutionized gene editing, having enormous research and clinical potential. However, gene editing can be tricky and have unexpected effects, like recently reported in the journal PNAS , where tweaking a gene produced aggressive hamsters instead of the calm, Zen animals the researchers were aiming for. Arginine-vasopressin (AVP) and […]

Epstein-Barr virus linked to multiple sclerosis

Epstein-Barr virus linked to multiple sclerosis

BiomedicineMedicine

By Rosa García-Verdugo

Multiple sclerosis (MS) is a debilitating autoimmune condition whereby neurons lose their myelin sheath leading to impaired neural transmission, neural degeneration and motor symptoms. Multiple factors have been considered to influence its development, like vitamin D, but now, a couple of studies have shown that the Epstein-Barr virus (EBV) is linked to multiple sclerosis. You […]

Healing from the skin: the first topical gene therapy is out

Healing from the skin: the first topical gene therapy is out

BiomedicineGenetics

By Rosa García-Verdugo

One of the biggest difficulties of bringing new therapeutic methods into clinical practice is targeted delivery. A recent study shows the potential of using a gel for topical gene therapy. Recessive dystrophic epidermolysis bullosa is a genetic disease that affects proper skin formation. The affected people have an extremely fragile skin, which often suffers from […]

Proteins can also act as brain messengers

Proteins can also act as brain messengers

Molecular biologyNeuroscience

By Rosa García-Verdugo

Brain cells communicate through neurotransmitters like glutamate or dopamine, the substances we got used to reading about when learning about brain function. However, it seems this is not the only way neurons can communicate. A new study suggests that certain proteins can act as brain messengers in the brain. Previously, only pathological proteins like tau […]

An ancient stress-related mechanism helps worms keep their cool

An ancient stress-related mechanism helps worms keep their cool

BiomedicineMolecular biology

By Rosa García-Verdugo

How an organism can sense and cope with warming temperatures is key for survival, particularly under current global warming trends. The importance of this subject was recognized by 2021’s Nobel prize in Physiology & Medicine awarded to work on TRP channels, key mammalian peripheral heat sensors. Endotherms -such as mammals and birds – maintain their […]