Category Archives: Genetics

Behind the symmetrical shell of humans and vertebrates lies a profound asymmetry. Our bilaterality breaks down inside our body. Not only our viscera are organized asymmetrically. Also our brain and nervous system, whose general appearance seems symmetrical, present lateralized structure […]

Patients suffering from rare diseases (defined by the European as those affecting less than 5 in 10000 people) have traditionally been overlooked by pharmaceutical companies. They are usually looking for the next blockbuster drug, so the lack of a […]

Pigmentations are among the clearest examples of phenotypic variation in many species. Hair, skin and eye colors are highly heritable and visible traits in humans. Blond hair is most commonly found in Northern and Central Europeans and their descendants. Nowadays […]

The identification of previously unknown proteins is a difficult task and often requires to follow unconventional thinking. In my previous post, I have described how the TRPV1 ion channel (formerly known as the capsaicin receptor) was discovered by combining the […]

Doing research in molecular biology is not straightforward, because most of the experimental work is based in the study of molecules which cannot be seen by the unaided eye. Instead, we rely on indirect evidence given by methods which are […]

Author: Koldo Garcia-Etxebarria got his Ph.D. in genetics at UPV/EHU in 2010. After a couple of years at the Evolutionary Biology Institute (CSIC-UPF) in Barcelona, he returned to UPV/EHU and joined José-Ramón Bilbao’s lab where he researches celiac disease. . Celiac […]

Since we were kids (unless under the spell of a creationist education), we have been told that genetics is the reason for the colour of our eyes, our hair, our height and whether we look more like mum or dad. […]

Autism is a highly prevalent spectrum disorder of the neurodevelopment. It is characterized by impaired social interaction, alterations in verbal and non-verbal communication, and restricted and repetitive behaviors. Considering these main differences, it had been difficult to have good […]

Laboratory mice are one of the most valuable tools scientists rely on to understand how pathologies work. In order to find a cure for a disease, we need to have comprehensive knowledge of the physiological processes which are impaired. […]

Author:. Ainara Castellanos-Rubio obtained her phD on genetics of autoimmune diseases at the University of the Basque Country in 2010. Then she moved to NY where she did her postdoctoral training in the laboratory of Prof. Sankar Ghosh at Columbia […]