T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy that results from transformation and clonal expansion of developmentally-arrested T-cell progenitors . Conventional risk-adjusted multi-agent chemotherapy allows for high 5-year event-free survival rates in children. However, a significant number of patients still relapse or do not respond to therapy. Consequently, there have been considerable efforts […]
A gauge theory is any number of quantum field theories put forward to explain fundamental interactions. In these theories the interactions between particles can be explained by the exchange of particles such as gluons, photons, and W and Z bosons. A gauge theory involves a symmetry group for the fields and potentials (the gauge group) […]
The 2024 Nobel Prizes in physics and chemistry have given us a glimpse of the future of science. Artificial intelligence (AI) was central to the discoveries honoured by both awards. You have to wonder what Alfred Nobel, who founded the prizes, would think of it all. We are certain to see many more Nobel medals […]
Climate change is increasingly influencing fire behaviour worldwide and intensifying fire smoke, endangering public health from air pollution caused by fires. These are the results of two new climate change impact attribution studies, both published in Nature Climate Change, with the involvement of the Potsdam Institute for Climate Impact Research PIK. The first study finds […]
Topological insulators are materials with special universal properties, which are protected against perturbations. Such properties are theoretically described by topology, a branch of mathematics concerned with the properties of geometrical objects that are unchanged by continuous deformations. Concretely, topological insulators are electronic materials that have a bulk band gap like an ordinary insulator but have […]
Author: Marc Zimmer, Professor of Chemistry, Connecticut College The 2024 Nobel Prize in chemistry recognized Demis Hassabis, John Jumper and David Baker for using machine learning to tackle one of biology’s biggest challenges: predicting the 3D shape of proteins and designing them from scratch. This year’s award stood out because it honored research that originated […]
The propagation of light -observed and governed since ancient times by simple lens construction- has long been described through classical geometrical optics. However, in particle accelerators we do not transport photons but beams of electrically charged particles subjected to repulsive forces that tend to unpack the particle beams. Optics of particle accelerators require electromagnetic lenses […]
A team of chemists at the Korea Advanced Institute of Science and Technology has succeeded in pulling an oxygen atom from a molecule and replacing it with a nitrogen atom. In their study, published in the journal Science, the group used photocatalysis to edit a furan in their lab. Ellie Plachinski and Tehshik Yoon with […]
Chemistry • DIPC Biochemistry • DIPC Computational and Theoretical Chemistry
Protein molecules consist of one or several long chains of aminoacids (usually between and 300 units) called polypeptides – a peptide is an organic compound comprising two or mores aminoacids – linked in a characteristic sequence. This sequence is called the primary structure of the protein. These polypeptides may undergo coiling or pleating, the nature […]
One of the hallmarks of aging is cognitive decline. New research in mice shows that long-term administration with tetrahydrocannabinol (THC), the primary psicoactive component of marihuana, at low doses can have antiaging-effects, particularly on cognitive decline. The endocannabinoid system (ECS) regulates various bodily and brain functions, including sleep, memory and learning, the immune system and […]