José R. Alonso has a PhD in Neurobiology and is professor of Cell Biology at the University of Salamanca. He has been researcher and visiting professor at the University of Frankfurt/Main and the University of Kiel, in Germany, and the University of California, Davis and the Salk Institute for Biological Studies, in the United States. He has authored more than 145 articles in peer-reviewed journals and written 20 books including university textbooks and popular science for both adults and children.
Lipids represent one of the fundamental molecular components within the realm of biological organisms, alongside proteins, carbohydrates, and nucleic acids. The concept of the “lipidome” pertains to the entirety of lipids found within a cell or a collection of cells. This terminology emerged within the context of modern biological sciences, often referred to as “omic […]
Health • Medicine • Physiology • Psychology
gender gap Sleep experts recommend that adults sleep 7-9 h per night (7-8 h for older adults). However, about 30-35% of adults sleep less than 7 h and prevalence rates of short or insufficient sleep are increasing. Insufficient sleep is not in itself a diagnosable disorder; however, its high prevalence highlights a key target for […]
Our body is at the core of our sense of self and our personal identity. However, the neural mechanisms underlying the conscious experience of our own body remain poorly understood. Partial or total anesthesia of the body does not lead to the disappearance of the bodily experience, but to a continued experience of the body’s […]
Serotonin or 5-hydroxytryptamine (5-HT) is a neurotransmitter involved in various cognitive and affective functions. Drugs targeting serotonin transmission, such as selective serotonin reuptake inhibitors (SSRIs), are the first-line pharmacological treatments for many neuropsychiatric disorders such as major depressive disorder, obsessive-compulsive disorder and anxiety. These antidepressants increase the concentration in the synaptic space of this neurotransmitter […]
In 1868, the famous, powerful and short French neurologist Jean-Martin Charcot, known as “the Napoleon of the Salpêtrière hospital”, described a new disease. He called it “sclerose en plaque” in reference to the numerous scars or sclerosis seen in the white matter of the brain and spinal cord. We now call it multiple sclerosis. Multiple […]
Pain is a complex sensation that is mediated by both the peripheral and central nervous systems. In the peripheral nervous system, pain signals are generated by nerve fibers called nociceptors that respond to harmful stimuli. These signals are then transmitted to the brain through the spinal cord, where they are processed and interpreted as pain […]
Occasionally I receive groups of messages from families with autistic members and I know the reason: they have read in the press exciting news about autism, a spectacular treatment, even a miracle cure. Unfortunately, if all that news were true we would have solved autism hundreds of times by now. So let’s start with the […]
For a long time, it was thought that dreaming occurred in the rapid eye movement phase of sleep (REM sleep). It is now well established that it can occur at any stage of sleep and, therefore, is not exclusive to a specific global vigilance state. Today, there is no known physiological correlate of a dream […]
Antidepressants are the mainstay for treating depression, but their use is clouded by doubts about their short-, medium- and long-term efficacy. This is not to say that we should not use them, as these drugs save lives in many cases, but a recent review reinforces these questions as it sees little difference in the quality […]
Witchcraft involves the use of magic or supernatural powers to harm others. In medieval and early modern Europe, where the term originated, those accused of witchcraft were usually women who were believed to have attacked their own community and often to be in communion with evil beings. Witchcraft powers were acquired by inheritance or initiation […]