Category archives: Biochemistry

A generalized approach for NMR studies of lipid–protein interactions

A generalized approach for NMR studies of lipid–protein interactions

BiochemistryChemistryMolecular biology

By Invited Researcher

Author: Francisco J. Blanco is an Ikerbasque Research Professor at CIC bioGUNE Molecular interactions in cell membranes, particularly lipid-protein interactions in their hydrophobic core, are difficult to analyse and remain poorly characterised despite high relevance in physiological and pathological processes. Structural rearrangements in membranes and embedded proteins, and the way molecular interactions contribute to their […]

The mechanochemistry of E. coli type 1 pilus

The mechanochemistry of E. coli type 1 pilus

BiochemistryBiomedicineMicrobiology

By DIPC

Uropathogenic Escherichia coli (UPEC) is responsible for approximately 90% of urinary tract infections (UTI) seen in individuals with an ordinary anatomy. In ascending infections, fecal bacteria colonize the urethra and spread up the urinary tract to the bladder as well as to the kidneys (causing pyelonephritis), o or the prostate in males. Because women have […]

A new theory on the early building blocks of life

A new theory on the early building blocks of life

BiochemistryBiologyChemistryEvolution

By Isabel Perez Castro

From nucleic acids to proteins and sugar chains, all life is made up of polymers, large molecules made up of sequences of small units called monomers. However, how these macromolecules first appeared on the surface of Earth is still controversial. It is generally assumed that, right before life started, our planet was covered in very […]

Modified DNA catalysts for chemical reactions in water

Modified DNA catalysts for chemical reactions in water

BiochemistryChemistryCondensed matterDIPC Biochemistry

By DIPC

We all know that the main role of DNA is the storage of genomic information leading to the biosynthesis of proteins via diverse forms of RNA. In turn, proteins play multiple roles in living systems, catalysis being among the most important ones. These are the standard functions that we may find in any general chemistry […]

Holidays, drug addiction…and cancer research

Holidays, drug addiction…and cancer research

BiochemistryBiomedicineMedicine

By Isabel Perez Castro

Cell signalling is the mechanism by which cells communicate with each other and with their environment. Stimuli, which are generally chemical, are transmitted via a signalling cascade to effector molecules that orchestrate the appropriate response. Signalling pathways are not isolated but they rather form a complex network of biochemical reactions that regulate processes such as […]