Category archives: Biochemistry

Holidays, drug addiction…and cancer research

Holidays, drug addiction…and cancer research

BiochemistryBiomedicineMedicine

By Isabel Perez Castro

Cell signalling is the mechanism by which cells communicate with each other and with their environment. Stimuli, which are generally chemical, are transmitted via a signalling cascade to effector molecules that orchestrate the appropriate response. Signalling pathways are not isolated but they rather form a complex network of biochemical reactions that regulate processes such as […]

Carotenoids, I see your true colours

Carotenoids, I see your true colours

BiochemistryChemistryPlant biology

By Estíbaliz Urarte

When autumn arrives to temperate climate forests, deciduous trees lose their characteristic green tonalities and start showing a wide spectrum of new colours: yellow, brown, orange, red… Chlorophyll reabsorption takes place in the leaves and carotenoids, present in a lower concentration, are exposed. These pigments are produced in all photosynthetic organisms, fungi and non-photosynthetic bacteria […]

Graphene nanopore DNA sequencing

Graphene nanopore DNA sequencing

BiochemistryChemistryCondensed matterMolecular biology

By Francisco R. Villatoro

Nanopore DNA sequencing was one the ten scientific breakthroughs of 2016 highlighted by Science magazine. In principle, graphene is the perfect pore material for DNA sequencing . Its monoatomic thickness of 0.35 nm is similar to the DNA base spacing and graphene nanopores can be fabricated with a diameter of only 1.0 nm, about the […]

SNPs, RNA and Celiac Disease

SNPs, RNA and Celiac Disease

BiochemistryBiomedicineGeneticsHealth

By Invited Researcher

Around 80% of the single nucleotide polymorphisms (SNPs) associated to many human diseases map to non-coding regions. Long non-coding RNAs (lncRNAs) represent a large portion of non-coding regions across the genome, however the link between the disease-associated SNPs on lncRNA expression or function, and the implications for disease, remain uncharacterized. Celiac disease is complex immune […]

Laforin, protein of the year

Laforin, protein of the year

BiochemistryMolecular biology

By Carlos Romá-Mateo

Unveiling the three-dimensional structure of proteins is one of the most useful strategies for understanding the molecular and cellular basis of human pathologies. Since proteins accomplish myriad cellular functions, but they are formed by combinations of only 20 different pieces, the way those pieces are coordinated is critical, and the tiniest difference can change forever […]

Opening the systemic avenue from chemistry to biology

Opening the systemic avenue from chemistry to biology

BiochemistryBiologyChemistryEvolution

By Invited Researcher

Author: Kepa Ruiz-Mirazo, Permanent Researcher, University of the Basque Country (UPV-EHU) Although «cracking the origins-of-life puzzle», regardless of the reputation of the journalist who tells the news, is clearly not within the reach of science quite yet, the article published a few weeks ago by Sutherland and colleagues in the UK , does constitute an […]