Category archives: Medicine

Mapping PTEN: basic research to assist precision oncology

Mapping PTEN: basic research to assist precision oncology

BiomedicineMedicineMolecular biology

By Invited Researcher

In the last two decades, the easiness in the obtaining of genetic information from patient biological samples, together with the advanced knowledge on the physiological consequences of patient genetic alterations, has transformed the daily clinical practice in our hospitals. As a result, the current use of the precision medicine concept, as disseminated today in the […]

Bacteria and cancer: the deadly mix

Bacteria and cancer: the deadly mix

BiomedicineMedicineMicrobiology

By Pasquale Pellegrini

Chemo-resistance remains a leading cause of mortality in cancer. Two recent discoveries demonstrate that some bacteria strains induce chemo-resistance, and can be targeted to increase the efficacy of therapeutic agents. The emerging relationship between the microorganisms and tumor progression has led many research groups to investigate whether the existence of a particular pattern of bacteria […]

Ayahuasca in the treatment of depression

Ayahuasca in the treatment of depression

HealthMedicineNeurosciencePharmacy

By José Ramón Alonso

Ayahuasca is an illegal entheogenic drug, substances that have the capacity to generate a mystical experience, a psychological sensation of contact with the divinity. Ayahuasca is an infusion prepared from the Banisteriopsis caapi liana and other ingredients, which include leaves of Psychotria viridis, Diplopyterys cabrerana and Mimosa tenuiflora. Psychotria has dimethyltryptamine (DMT), a strongly psychoactive […]

Optimizing arrythmia ablation

Optimizing arrythmia ablation

MathematicsMedicine

By BCAM

The heart is a muscular organ with four chambers designed to work efficiently, reliably, and continuously over a lifetime. The muscular walls of each chamber contract in a regulated sequence, pumping blood as required by the body while expending as little energy as possible during each heartbeat. Contraction of the muscle fibres in the heart […]

Enzybiotics, from phages to the inhaler.

Enzybiotics, from phages to the inhaler.

BiomedicineMedicineMicrobiologyPharmacy

By Invited Researcher

In the age of bacteria resistant to multiple antibiotics, the so-called superbacteria, it is critical to our future the development of novel therapeutic strategies. Lytic enzymes encoded by bacteriophages – viruses that specifically kill bacteria, also called lysins or enzybiotics, are effective agents for preventing and controlling diseases caused by Gram+ bacteria, including Streptococcus pneumoniae […]

Is cancer a side effect of the treatment of cardiac problems in children?

Is cancer a side effect of the treatment of cardiac problems in children?

MathematicsMedicine

By BCAM

Why people younger than 22 with congenital or acquired heart conditions should be more likely of developing a cancer? Actually, a small number of studies have been published, suggesting relatively high cancer incidence and mortality, compared to the general population. If it is true a correlation exists, there are several potential explanations. It could be […]

Augmented reality and autism

Augmented reality and autism

HealthMedicineNeurobiologyNeuroscience

By José Ramón Alonso

The most effective interventions in people with autism are based on a personal work by specialized professionals and these therapies, when well designed and well done, achieve a constant improvement in different areas such as social communication, the presence of stereotypes and other atypical behaviors characteristic of autism. However, person-to-person therapies are by their very […]

Nociceptor inhibition as a new therapeutic approach for asthma

Nociceptor inhibition as a new therapeutic approach for asthma

BiomedicineMedicineNeurobiologyPharmacy

By Sergio Laínez

When we hear somebody wheezing, coughing, showing chest tightness and shortness of breath, most of us will immediately recognize the underlying cause: Asthma. This is not a minor issue, but one affecting approximately 5% of the entire world population (and steeply growing every year) and causing the death of nearly 400000 people back in 2015 […]

Novel strategies to selectively reduce pain

Novel strategies to selectively reduce pain

MedicineNeurobiologyPharmacy

By Sergio Laínez

A recurrent problem with pain is the absence of therapeutic strategies to selectively block the nociceptors (neurons responsible to detect painful stimuli) that need to be targeted for a particular indication. Things get even worse if we take into account that some molecules used for pain management do affect other, more general physiological processes. Local […]