Author: Ramón Muñoz-Chápuli has been Professor of Animal Biology in the University of Málaga until his retirement. He has investigated for forty years in the fields of developmental biology and animal evolution. Lungfish (Dipnoi) are fascinating animals. Despite having gills, they can breathe atmospheric air thanks to a pair of lungs. Their geographic distribution aligns […]
Chromatin is a complex of DNA and histone, a protein, in the nucleus of a cell. One of the main functions of chromatin is to help DNA packing. Cellular phenotypic heterogeneity is a key determinant of many biological functions; yet, it is still not clear whether it stems from the modifications of the chromatin structure […]
Many (if not most) clinical trials end up failing, but given the bias towards positive results sometimes the reasons for their not working remain unclear. Luckily, a team at Open Targets and EMBL’s European Bioinformatics Institute (EMBL-EBI) have analysed the reasons for aborted clinical trials mentioned in Clinicaltrials.gov, the open-source register for clinical trials worldwide […]
Authors: Eva-Maria Geigl, Directrice de recherche CNRS, co-responsable de l’équipe Épigénome et paléogénome de l’Institut Jacques Monod, Université Paris Cité; Oğuzhan Parasayan, Chercheur post-doctoral, Institut Pasteur, and Thierry Grange, Directeur de Recherche CNRS, co-responsable d’équipe de recherche, Institut Jacques Monod, Université Paris Cité High-resolution analysis of the genomes of individuals buried in a 4,500-year-old collective […]
The evolution of the human being has a complex form in which some branches bifurcate and form two different species and some different branches come together again and form individuals with a certain degree of hybridization. The only hominin remaining today is Homo sapiens and the last to disappear was Homo neanderthalensis. Neanderthals, our closest […]
Our DNA is a puzzle resulting from millions of years of evolution. An ancient part of it is composed of the genetic material of viruses that integrated in our genome and became part of “us.” Though it may seem strange, about 7% of our genomes are comprised by these old viral sequences. What’s more, recent […]
Roundworms are the most commonly used animal model to investigate aging and methods to increase the lifespan such as intermittent fasting. Latest research indicates that jumping genes could be another target for interventions aiming towards expanding the lifespan. What are jumping genes? Also called transposons, are movable stretches of DNA of possible viral origin that […]
Cell division, or mitosis, is a breathtaking choreography that showcases the grandeur of life. The primary objective of this process is to meticulously separate the two copies of the cell genome, presented in the form of chromatin, and allocate them between two daughter cells. Consequently, it holds paramount significance for the reproduction of unicellular organisms […]
So far, contraception has been practically exclusive to women. They are the ones not only responsible for the matter, but also the ones to suffer the brunt of the side effects of current contraceptive methods. Arrdc5, a new gene identified in mice, might hold the key to male contraception. This gene, common to several mammal […]
Author: Ramón Muñoz-Chápuli has been Professor of Animal Biology in the University of Málaga until his retirement. He has investigated for forty years in the fields of developmental biology and animal evolution. Hummingbirds are fascinating animals. They are the only birds able to true hovering and backward flight. This ability allows them to collect nectar […]