Computer science • Genetics • Health • Medicine • Molecular biology • Pharmacy
A number of technologies and tools got a chance to prove themselves for the first time in the context of COVID-19. Three researchers working in gene-based vaccines, wearable diagnostics and drug discovery explain how their work rose to the challenge of the pandemic, and their hopes that each technology is now poised to continue making […]
Hollywood blockbusters such as X-men, Gattaca and Jurassic World have explored the intriguing concept of “germline genome editing” – a biomolecular technique that can alter the DNA of sperm, eggs or embryos. If you remove a gene that causes a certain disease in an embryo, not only will the baby be free of the disease […]
Loss of gene function is a common occurrence in evolution that is usually associated with loss of fitness. However, it seems that as many say: “where there’s a problem, there is an opportunity“, for as researchers from Leuven University led by Rob Jelier have recently reported , gene loss was found to drive adaptation. To […]
It seems that the genetic risk of an APOE4 variant in the APOE gene would not only increase risk for Alzheimer’s but also would increase the chances of getting infected by the COVID-19 virus. The APO protein is involved in cholesterol metabolism and the immune system. However, its precise role in Alzheimer’s disease is as […]
Gene therapy was a 90s hit. The most promising medical advance of the decade was almost forgotten after some really serious side effects occurred in one clinical trial, but after nearly 3 decades a small trial in Germany has shown gene therapy not only to be safe for use in humans but also to have […]
A reported case study in a Colombian woman , member of a family carriers of a mutation in the presinilin 1 gene which leads to early onset Alzheimer’s, has shown that a certain mutation in the gene APOE3 can protect from the cognitive decline associated with Alzheimer’s disease. This woman was already aged 70 but […]
Believe it to not, little worms (C.elegans) are an useful tool for researchers studying aging. Specially, the genetics of aging. A recently released article in Cell Reports shows that gene modification in two specific cellular pathways drives 500% life extension in worms. Why worms? Worms are the ideal research subject for aging and genetics because […]
The question of whether it is genes or environment that largely shapes human behaviour has been debated for centuries. During the second half of the 20th century, there were two camps of scientists – each believing that nature or nurture, respectively, was exclusively at play. This view is becoming increasingly rare, as research is demonstrating […]
That female fertility is not stable during a woman’s lifetime is nothing new, but now a new study in the journal Science has found an explanation to its inverted U shape: chromosome errors! This inverted U shape for female fertility means that adolescent women and women over their mid-30s are not as fertile as those […]
An allele is each of the alternative forms that the same gene can have. The alleles differ in their DNA sequence and can manifest in different results after expressing that gene, such as differences in the color of the eyes or in the blood group. Human beings are diploid, we have two sets of chromosomes […]