It seems that the genetic risk of an APOE4 variant in the APOE gene would not only increase risk for Alzheimer’s but also would increase the chances of getting infected by the COVID-19 virus. The APO protein is involved in cholesterol metabolism and the immune system. However, its precise role in Alzheimer’s disease is as […]
Gene therapy was a 90s hit. The most promising medical advance of the decade was almost forgotten after some really serious side effects occurred in one clinical trial, but after nearly 3 decades a small trial in Germany has shown gene therapy not only to be safe for use in humans but also to have […]
A reported case study in a Colombian woman , member of a family carriers of a mutation in the presinilin 1 gene which leads to early onset Alzheimer’s, has shown that a certain mutation in the gene APOE3 can protect from the cognitive decline associated with Alzheimer’s disease. This woman was already aged 70 but […]
Believe it to not, little worms (C.elegans) are an useful tool for researchers studying aging. Specially, the genetics of aging. A recently released article in Cell Reports shows that gene modification in two specific cellular pathways drives 500% life extension in worms. Why worms? Worms are the ideal research subject for aging and genetics because […]
The question of whether it is genes or environment that largely shapes human behaviour has been debated for centuries. During the second half of the 20th century, there were two camps of scientists – each believing that nature or nurture, respectively, was exclusively at play. This view is becoming increasingly rare, as research is demonstrating […]
That female fertility is not stable during a woman’s lifetime is nothing new, but now a new study in the journal Science has found an explanation to its inverted U shape: chromosome errors! This inverted U shape for female fertility means that adolescent women and women over their mid-30s are not as fertile as those […]
An allele is each of the alternative forms that the same gene can have. The alleles differ in their DNA sequence and can manifest in different results after expressing that gene, such as differences in the color of the eyes or in the blood group. Human beings are diploid, we have two sets of chromosomes […]
Recent research by a collaborative research network including researchers in Spain and the UK has found 25 genes that seem to be responsible for making humans the primates with the longest life spans (sometimes going up to 120 years). These genes show parallel mutations in genes related to wound healing, blood coagulation and cardiovascular disorders […]
Educational attainment, the years a person spends within the education system, generates interest among scientists because statistical analysis shows that there is a relationship between that value and different aspects of life including income when adults, state of health and even life expectancy. Geneticists analyze trends that can explain variations within a population by exploring […]
The haploid human genome contains approximately 3,000,000,000 base pairs of DNA packaged into 23 chromosomes. Most cells in the body, except for eggs and sperm, are diploid, with 23 pairs of chromosomes. That makes a total of 6,000,000,000 base pairs of DNA per cell that, if they were to be put in a straight line […]