Biology • Biotechnology • Ethics • Evolution • Genetics
Ever since the 1993 film based on Michael Crichton’s novel Jurassic Park was released, the thought of reviving extinct species using molecular biology techniques has been on the forefront of the collective imaginary. The idea seemed pretty simple: reading the genetic code of fossilized animals would provide the instruction manual to bring them back to […]
Plants are sessile organisms, which means they can´t move around. Of course, they have some types of movements like turning towards the sun but the place where the seed germinates the plant will stay during their entire life cycle. Obviously, this fact has important consequences on how plants respond upon variations of their surrounding environment […]
The scientific community, in their different fields and specialties, has made tremendous progress regarding human health and how we deal with all the maladies affecting mankind. Particularly in cancer, the Pulitzer Prize-winning book entitled “The Emperor of All Maladies” summarizes in a marvelous way this notion. However, I am convinced that our struggle against cancer […]
Back in 2001, the Human Genome Project gave us a complete readout of our DNA, unraveling that magic sequence of As, Gs, Cs, and Ts that contained all the information for making one of us. Thanks to that, we now know that in that sequence only 1.5% has information to make proteins, a fact that […]
Since the cells were discovered with the advent of the microscope in the late seventeenth century, scientists have tried hard to find out what is going on into them. An avalanche of techniques and technologies emerged over the course of decades slowly discovering important molecular features of the cellular world to our knowledge and our […]
Photoreceptor degeneration is one of the most common causes of partial as well as total blindness. However, one of its “positive” -or at least, not so negative- characteristics is that, while light-sensing photoreceptor cells in the surface of the retina are damaged, the inner retinal cell layers and the central visual pathways remain intact over […]
Most famous RNAs are coding or messenger RNAs (mRNAs) which are the ones that ribosomes read to synthesize proteins. However, many other RNAs are transcribed from DNA and are known as non-coding RNAs. Among those, ribosomic RNAs (rRNAs) which are part of the ribosomes and transfer RNAs (tRNAs) which deliver the amino acids to the […]
The term epigenetics refers to heritable changes in gene expression (active vs. inactive genes) that does not involve changes to the underlying DNA sequence. It results in change in phenotype without a change in genotype. An easily comprehensible example are identical twins: since they develop from a single fertilized egg, they have the same genome […]
We all have listened about gene therapy, and for those who are old enough not in a good way, at all. Gene therapy became the most promising clinical therapy in the 1990s and this technology was meant to transform medicine. In essence, the concept of gene therapy is pretty simple: the introduction of an exogenous […]
Last Friday I was, as is always the case listening to an enthusiastic talk given by one of the PhD students from my department. As part of her PhD work, she is trying to understand why periodontitis, an inflammatory disease where gums get swollen as a consequence of bacterial infection, is essentially painless. This is […]