Category archives: Neurobiology

Lysosomes: the Achilles heel of brain macrophages during a stroke

Lysosomes: the Achilles heel of brain macrophages during a stroke

NeurobiologyNeuroscience

By Invited Researcher

The brain tissue is filled by cells, the living units that enable function; the extracellular matrix, the scaffold wherein cells organize; and the blood vessels, which transport metabolic fuels such as oxygen and nutrients to the brain. Among the brain cells, we find the neurons, highly specialized cells that transmit information; and the glial cells […]

A single gene might be responsible for the bigger brain of modern humans

A single gene might be responsible for the bigger brain of modern humans

EvolutionGeneticsNeurobiology

By Rosa García-Verdugo

We, humans, have evolved pretty big brains compared to other mammals, and even compared to our primate cousins. Recent research seems to have found the reason for the higher number of neurons in our brains (about 86 billion). It appears that a single gene is responsible for our bigger brain. The Neanderthals are an extinct […]

Pain and autism

Pain and autism

Neurobiology

By José Ramón Alonso

Pain is a complex sensation that is mediated by both the peripheral and central nervous systems. In the peripheral nervous system, pain signals are generated by nerve fibers called nociceptors that respond to harmful stimuli. These signals are then transmitted to the brain through the spinal cord, where they are processed and interpreted as pain […]

Electrical stimulation allows nine paralysed patients to walk

Electrical stimulation allows nine paralysed patients to walk

MedicineNeurobiologyNeuroscience

By Rosa García-Verdugo

Electrical stimulation of the spinal cord can help recover mobility in some paralysed patients. However, the mechanism underlying this partial recovery of function remains unknown. A recent human study has confirmed the involvement of a group of cells previously identified in mice, paving the way to targeted treatments. In a recently published study in Nature […]

Neuroplasticity: Word and face recognition with half a brain

Neuroplasticity: Word and face recognition with half a brain

NeurobiologyNeuroscience

By César Tomé

An unprecedented study of brain plasticity and visual perception found that people who, as children, had undergone surgery removing half of their brain correctly recognized differences between pairs of words or faces more than 80% of the time. Considering the volume of removed brain tissue, the surprising accuracy highlights the brain’s neuroplasticity– and its limitations […]

Alzheimer’s disease: Is amyloid beta 42 the answer?

Alzheimer’s disease: Is amyloid beta 42 the answer?

BiomedicineMedicineNeurobiology

By Invited Researcher

In 1906, Alois Alzheimer, a psychiatrist and neuroanatomist, reported “a peculiar severe disease process of the cerebral cortex” to a gathering of psychiatrists in Tübingen, Germany. The case was a 50-year-old woman who suffered from memory loss, delusions, hallucinations, aggression and confusion – all of which worsened until her untimely death five years later. In […]