Category archives: Neurobiology

Psychosis and brain structure

Psychosis and brain structure

Neurobiology

By José Ramón Alonso

One of the intriguing and central mysteries in contemporary neuroscience revolves around the intricate relationship between the brain and the mind. While our understanding of neurons, neurotransmitters, and neuronal receptors has advanced significantly, the elusive question remains: How do these complex chemical and electrical processes translate into thoughts, emotions, and behaviors? Gaining insight into these […]

Platelets participate in hippocampal neurogenesis and cognitive function

Platelets participate in hippocampal neurogenesis and cognitive function

BiologyBiomedicineNeurobiology

By Invited Researcher

Platelets Author: José R. Pineda got his Ph.D. from University of Barcelona in 2006. Since 2007 he has worked for Institut Curie and The French Alternative Energies and Atomic Energy Commission. Currently he is a researcher of the UPV/EHU. He investigates the role of stem cells in physiologic and pathologic conditions. There is currently a […]

Lipids and autism

Lipids and autism

Neurobiology

By José Ramón Alonso

Lipids represent one of the fundamental molecular components within the realm of biological organisms, alongside proteins, carbohydrates, and nucleic acids. The concept of the “lipidome” pertains to the entirety of lipids found within a cell or a collection of cells. This terminology emerged within the context of modern biological sciences, often referred to as “omic […]

A lifetime of mental illness accelerates ageing

A lifetime of mental illness accelerates ageing

NeurobiologyNeuroscience

By Rosa García-Verdugo

Mental illness is associated with accelerated ageing, namely with shorter life span and ageing-related diseases such as diabetes or cardiovascular problems, with worse effects observed in men than women (the average lifespan for men having suffered from mental illness is 10 years shorter than for peers without those issues, for women the difference is seven […]

Emotional dampening of antidepressants

Emotional dampening of antidepressants

MedicineNeurobiologyNeurosciencePharmacy

By José Ramón Alonso

Serotonin or 5-hydroxytryptamine (5-HT) is a neurotransmitter involved in various cognitive and affective functions. Drugs targeting serotonin transmission, such as selective serotonin reuptake inhibitors (SSRIs), are the first-line pharmacological treatments for many neuropsychiatric disorders such as major depressive disorder, obsessive-compulsive disorder and anxiety. These antidepressants increase the concentration in the synaptic space of this neurotransmitter […]

Lysosomes: the Achilles heel of brain macrophages during a stroke

Lysosomes: the Achilles heel of brain macrophages during a stroke

NeurobiologyNeuroscience

By Invited Researcher

The brain tissue is filled by cells, the living units that enable function; the extracellular matrix, the scaffold wherein cells organize; and the blood vessels, which transport metabolic fuels such as oxygen and nutrients to the brain. Among the brain cells, we find the neurons, highly specialized cells that transmit information; and the glial cells […]

A single gene might be responsible for the bigger brain of modern humans

A single gene might be responsible for the bigger brain of modern humans

EvolutionGeneticsNeurobiology

By Rosa García-Verdugo

We, humans, have evolved pretty big brains compared to other mammals, and even compared to our primate cousins. Recent research seems to have found the reason for the higher number of neurons in our brains (about 86 billion). It appears that a single gene is responsible for our bigger brain. The Neanderthals are an extinct […]

Pain and autism

Pain and autism

Neurobiology

By José Ramón Alonso

Pain is a complex sensation that is mediated by both the peripheral and central nervous systems. In the peripheral nervous system, pain signals are generated by nerve fibers called nociceptors that respond to harmful stimuli. These signals are then transmitted to the brain through the spinal cord, where they are processed and interpreted as pain […]