Category archives: Biomedicine

Immune-based therapies to fight leukemia

Immune-based therapies to fight leukemia

BiomedicineMedicine

By Invited Researcher

Acute leukemia is characterized by the proliferation and accumulation of hematopoietic progenitor cells (which are able to differentiate to create specialized cell types) in the bone marrow that impede normal blood production. D epending on the cell population affected, it can be classified in Acute Lymphoblastic Leukemia (ALL) and Acute Myeloid Leukemia (AML). ALL starts […]

Model of new tuberculosis vaccine shows its potential impact and value in South Africa and India

Model of new tuberculosis vaccine shows its potential impact and value in South Africa and India

BiomedicineMedicine

By Invited Researcher

Two years of battling COVID-19 has been bad news for tuberculosis (TB) programmes. Respiratory clinicians and researchers have had their time and focus directed elsewhere. And TB has taken advantage. In 2021, the number of TB deaths rose for the first time in over a decade. The barriers caused by lockdowns and overstretched healthcare systems […]

How to regenerate a functional heart using 3D printing

How to regenerate a functional heart using 3D printing

BiomedicineMaterials

By Invited Researcher

C ardiovascular diseases currently form the most important class of non-contagious diseases and a leading cause of mortality in industrialized nations . Specifically, coronary heart disease is the first cause of death among the cardiovascular diseases . The myocardial infarction (MI), commonly known as a “heart attack”, occurs when blood flow decreases or stops in […]

An ancient stress-related mechanism helps worms keep their cool

An ancient stress-related mechanism helps worms keep their cool

BiomedicineMolecular biology

By Rosa García-Verdugo

How an organism can sense and cope with warming temperatures is key for survival, particularly under current global warming trends. The importance of this subject was recognized by 2021’s Nobel prize in Physiology & Medicine awarded to work on TRP channels, key mammalian peripheral heat sensors. Endotherms -such as mammals and birds – maintain their […]

New gene variants associated with increased COVID-19 risk

New gene variants associated with increased COVID-19 risk

BiomedicineGenetics

By Rosa García-Verdugo

Since the beginning of the COVID-19 pandemic, there were hints at particular genes which increased some people’s susceptibility to get infected and the severity of illness once infected. Now, an international study (nearly 3500 researchers from 25 countries) on more than 45000 people infected with SARS-CoV-2, showed a link between 13 genetic variants and the […]

When the inhibition of the inhibitory signals results in an exacerbated response. The case of IL-13 and the COVID-19 severity.

When the inhibition of the inhibitory signals results in an exacerbated response. The case of IL-13 and the COVID-19 severity.

Biomedicine

By Invited Researcher

Author: José R. Pineda got his Ph.D. from University of Barcelona in 2006. Since 2007 he has worked for Institut Curie and The French Alternative Energies and Atomic Energy Commission. Currently he is a researcher of the UPV/EHU. He investigates the role of stem cells in physiologic and pathologic conditions. A long time ago, I […]

Gene editing could help reverse fast ageing in progeria

Gene editing could help reverse fast ageing in progeria

BiomedicineGenetics

By Rosa García-Verdugo

Gene editing could be the solution to progeria, a genetic disease, characterized by extremely fast ageing. Progeria causes fast ageing and premature death in people carrying a single-point mutation in the LMNA gene, which basically leads to the production of a toxic protein which slowly damages the cells, ageing the bodies. This simple misspelling of […]