Category archives: Biomedicine

Chromatic multiphoton serial microscopy can generate brain-wide atlas-like colour datasets with subcellular resolution

Chromatic multiphoton serial microscopy can generate brain-wide atlas-like colour datasets with subcellular resolution

BiologyBiomedicineComputer scienceNanotechnologyNeurosciencePhysics

By DIPC

In 1873, the microscopist Ernst Abbe stipulated a physical limit for the maximum resolution of traditional optical microscopy: 0.2 micrometers, or 200 nanometers (the shortest wavelength for visible light, the extreme limit of violet). This meant that scientists could distinguish whole cells, as well as some parts of the cell called organelles. However, they would […]

Mapping PTEN: basic research to assist precision oncology

Mapping PTEN: basic research to assist precision oncology

BiomedicineMedicineMolecular biology

By Invited Researcher

In the last two decades, the easiness in the obtaining of genetic information from patient biological samples, together with the advanced knowledge on the physiological consequences of patient genetic alterations, has transformed the daily clinical practice in our hospitals. As a result, the current use of the precision medicine concept, as disseminated today in the […]

Bacteria and cancer: the deadly mix

Bacteria and cancer: the deadly mix

BiomedicineMedicineMicrobiology

By Pasquale Pellegrini

Chemo-resistance remains a leading cause of mortality in cancer. Two recent discoveries demonstrate that some bacteria strains induce chemo-resistance, and can be targeted to increase the efficacy of therapeutic agents. The emerging relationship between the microorganisms and tumor progression has led many research groups to investigate whether the existence of a particular pattern of bacteria […]

TRAMIL: Program of Applied Research to Popular Medicine in the Caribbean

TRAMIL: Program of Applied Research to Popular Medicine in the Caribbean

BiologyBiomedicineHealthPlant biology

By Gerardo Cebrián

Authors: Gerardo Cebrián-Torrejón1, Michelle Salas Pinel1,2 1 Laboratoire COVACHIM-M2E EA 3592, Université des Antilles, 97157 Pointe-à-Pitre Cedex. 2 Forest engineer. Heredia. Costa Rica. The Applied Scientific Research Program of Medicinal Plants, known as TRAMIL, is an investigation program of traditional and popular medicine from the Caribbean, whose purpose is to rationalize health practices based on […]

Enzybiotics, from phages to the inhaler.

Enzybiotics, from phages to the inhaler.

BiomedicineMedicineMicrobiologyPharmacy

By Invited Researcher

In the age of bacteria resistant to multiple antibiotics, the so-called superbacteria, it is critical to our future the development of novel therapeutic strategies. Lytic enzymes encoded by bacteriophages – viruses that specifically kill bacteria, also called lysins or enzybiotics, are effective agents for preventing and controlling diseases caused by Gram+ bacteria, including Streptococcus pneumoniae […]

How maternal vaginal microbiome can bring you to madness

How maternal vaginal microbiome can bring you to madness

BiologyBiomedicineMicrobiologyNeurobiology

By Raúl Delgado-Morales

Maternal and paternal stress have been proved to be critical aspects of off-spring brain development. High levels of stress on pregnant mothers can alter both placental and embryonic gene expression patterns, misprogramming the brain of the newborn towards psychiatric disorders such as anxiety or depression. At the same level, paternal stress alters microRNAs and other […]