Category archives: Biomedicine

Platelets participate in hippocampal neurogenesis and cognitive function

Platelets participate in hippocampal neurogenesis and cognitive function

BiologyBiomedicineNeurobiology

By Invited Researcher

Platelets Author: José R. Pineda got his Ph.D. from University of Barcelona in 2006. Since 2007 he has worked for Institut Curie and The French Alternative Energies and Atomic Energy Commission. Currently he is a researcher of the UPV/EHU. He investigates the role of stem cells in physiologic and pathologic conditions. There is currently a […]

Cutaneous lymphocyte antigen is a potential therapeutic target in cutaneous T-cell lymphoma

Cutaneous lymphocyte antigen is a potential therapeutic target in cutaneous T-cell lymphoma

Biomedicine

By Invited Researcher

Cutaneous Author: Marta Irigoyen is a postdoctoral researcher at CIC bioGUNE Cutaneous T-cell lymphoma (CTCL) is a rare type of cancer that begins in white blood cells called T cells (T lymphocytes). These cells normally help the body’s immune system to fight germs and pathogens. In cutaneous T-cell lymphoma, T cells acquire aberrant functions that […]

Inhibition of Hypoxia-Inducible Factor Alpha (HIF-1α) helps suppress T-ALL drug resistance

Inhibition of Hypoxia-Inducible Factor Alpha (HIF-1α) helps suppress T-ALL drug resistance

Biomedicine

By Invited Researcher

Hypoxia Author: Marta Irigoyen is a postdoctoral researcher at CIC bioGUNE Despite the fact that c ancer treatments have greatly improved during recent years, chemoresistance remains a major problem in eradicating cancer cells. Drug resistance involves not only many cell intrinsic mechanisms but also extrinsic induced chemoprotection by the tumor microenvironment . In fact, this […]

New generation sensors for the prevention of the next pandemic

New generation sensors for the prevention of the next pandemic

BiomedicineMaterialsMedicine

By BCMaterials

The recent COVID-19 pandemic has demonstrated the vulnerabilities of our society to infectious diseases and the limitations of the tools available for viruses detection. Polymerase chain reaction (PCR) and antigens tests have been useful to monitor and contain the extension of the last pandemic, however it demonstrated to have severe limitations. PCR is a highly […]

A new imaging technique allows visualisation inside intact animals

A new imaging technique allows visualisation inside intact animals

BiomedicineMolecular biology

By Rosa García-Verdugo

One of the biggest challenges of medical imaging technologies is actually resolving the structures of interest, be it a tumour, a lung or a blood vessel, without the “noise” from other bodily parts like skin or muscle. A new imaging technique allows for visualisation inside intact animals at higher resolution than ever before. A team […]

T-cell acute leukaemia exhibits dynamic interactions with bone marrow microenvironment

T-cell acute leukaemia exhibits dynamic interactions with bone marrow microenvironment

Biomedicine

By Invited Researcher

T-cell Author: Marta Irigoyen is a postdoctoral researcher at CIC bioGUNE T-ALL is an aggressive malignancy which results from the leukemic transformation of T-cell progenitors into tumor cells. It is widely accepted that complex interactions between T-ALL cells and their surrounding microenvironment contribute to disease and may regulate quiescence, survival and self-renewal of cancer cells […]

Obesity hinders brain recognition of nutrient signals

Obesity hinders brain recognition of nutrient signals

BiochemistryBiomedicineHealthMedicineNeuroscience

By Rosa García-Verdugo

Recent research has demonstrated that obesity impairs the mechanisms that allow our brains to realize when our stomachs are full and that these changes are maintained despite dieting, giving insights into why it is difficult for obese people to avoid excessive eating and why there is often a yo-yo effect after dieting. It has been […]

SARS-CoV-2 infect immune cells of the central nervous system

SARS-CoV-2 infect immune cells of the central nervous system

BiomedicineNeuroscience

By Invited Researcher

SARS-CoV-2 Author: José R. Pineda got his Ph.D. from University of Barcelona in 2006. Since 2007 he has worked for Institut Curie and The French Alternative Energies and Atomic Energy Commission. Currently he is a researcher of the UPV/EHU. He investigates the role of stem cells in physiologic and pathologic conditions. With 676.609.955 cases registered […]

A dog parasite could help fight incurable cancers

A dog parasite could help fight incurable cancers

BiologyBiomedicineMedicine

By Invited Researcher

Cancers are the second leading cause of death in the world, after cardiovascular diseases. Their seriousness lies in their diversity – some can be effectively treated with surgery, chemotherapy and radiotherapy, while others respond poorly or not at all. Improving the treatment of these diseases is therefore a major challenge. For several years, the development […]