Category archives: Biomedicine

In 1873, the microscopist Ernst Abbe stipulated a physical limit for the maximum resolution of traditional optical microscopy: 0.2 micrometers, or 200 nanometers (the shortest wavelength for visible light, the extreme limit of violet). This meant that scientists could distinguish whole cells, as well as some parts of the cell called organelles. However, they would […]

In the last two decades, the easiness in the obtaining of genetic information from patient biological samples, together with the advanced knowledge on the physiological consequences of patient genetic alterations, has transformed the daily clinical practice in our hospitals. As a result, the current use of the precision medicine concept, as disseminated today in the […]

Chemo-resistance remains a leading cause of mortality in cancer. Two recent discoveries demonstrate that some bacteria strains induce chemo-resistance, and can be targeted to increase the efficacy of therapeutic agents. The emerging relationship between the microorganisms and tumor progression has led many research groups to investigate whether the existence of a particular pattern of bacteria […]

Authors: Gerardo Cebrián-Torrejón 1, Michelle Salas Pinel 1,2 1 Laboratoire COVACHIM-M2E EA 3592, Université des Antilles, 97157 Pointe-à-Pitre Cedex. 2 Forest engineer. Heredia. Costa Rica. The Applied Scientific Research Program of Medicinal Plants, k nown as TRAMIL, is an investigation program of traditional and popular medicine from the Caribbean, whose purpose is to rationalize health […]

An allele is each of the alternative forms that the same gene can have. The alleles differ in their DNA sequence and can manifest in different results after expressing that gene, such as differences in the color of the eyes or in the blood group. Human beings are diploid, we have two sets of chromosomes […]

I n the age of bacteria resistant to multiple antibiotics, the so-called superbacteria, it is critical to our future the development of novel therapeutic strategies. Lytic enzymes encoded by bacteriophages – viruses that specifically kill bacteria, also called lysins or enzybiotics, are effective agents for preventing and controlling diseases caused by Gram+ bacteria, including Streptococcus […]

Maternal and paternal stress have been proved to be critical aspects of off-spring brain development. High levels of stress on pregnant mothers can alter both placental and embryonic gene expression patterns, misprogramming the brain of the newborn towards psychiatric disorders such as anxiety or depression. At the same level, paternal stress alters microRNAs and other […]

Uropathogenic Escherichia coli (UPEC) is responsible for approximately 90% of urinary tract infections (UTI) seen in individuals with an ordinary anatomy. In ascending infections, fecal bacteria colonize the urethra and spread up the urinary tract to the bladder as well as to the kidneys (causing pyelonephritis), o or the prostate in males. Because women have […]

Little children with autism have more lead and less zinc and manganese than children of the same age without autism. The study has been published in the journal Nature Communications and has been carried out by a team from the National Institute of Environmental Health Sciences (NIEHS), part of the National Institutes of Health (NIH) […]

Author: Iker Badiola is an assistant professor in the Department of Cell Biology and Histology, Faculty of Medicine and Nursery, University of Basque Country (UPV/EHU). Colorectal cancer is the third most frequently occurring cancer and a common cause of cancer-related death worldwide. The origin of colorectal cancer is usually a malignant polyp developed in the […]