Category archives: Microbiology

Enzybiotics, from phages to the inhaler.

Enzybiotics, from phages to the inhaler.

BiomedicineMedicineMicrobiologyPharmacy

By Invited Researcher

I n the age of bacteria resistant to multiple antibiotics, the so-called superbacteria, it is critical to our future the development of novel therapeutic strategies. Lytic enzymes encoded by bacteriophages – viruses that specifically kill bacteria, also called lysins or enzybiotics, are effective agents for preventing and controlling diseases caused by Gram+ bacteria, including Streptococcus […]

How maternal vaginal microbiome can bring you to madness

How maternal vaginal microbiome can bring you to madness

BiologyBiomedicineMicrobiologyNeurobiology

By Raúl Delgado-Morales

Maternal and paternal stress have been proved to be critical aspects of off-spring brain development. High levels of stress on pregnant mothers can alter both placental and embryonic gene expression patterns, misprogramming the brain of the newborn towards psychiatric disorders such as anxiety or depression. At the same level, paternal stress alters microRNAs and other […]

The mechanochemistry of E. coli type 1 pilus

The mechanochemistry of E. coli type 1 pilus

BiochemistryBiomedicineMicrobiology

By DIPC

Uropathogenic Escherichia coli (UPEC) is responsible for approximately 90% of urinary tract infections (UTI) seen in individuals with an ordinary anatomy. In ascending infections, fecal bacteria colonize the urethra and spread up the urinary tract to the bladder as well as to the kidneys (causing pyelonephritis), o or the prostate in males. Because women have […]

The rise of the superbugs

The rise of the superbugs

MicrobiologyPharmacy

By Sergio Laínez

Our society will be facing a number of health-related challenges in the near future, partly as a consequence of our own practices. Perhaps the best known examples are the (severe) health issues linked to smoking (not just to smokers, but also their children via epigenetic changes) or the abnormally high intake of carbohydrates, with the […]

Combatting antimicrobial resistance with a ruthenium-based photorelease antimicrobial therapy

Combatting antimicrobial resistance with a ruthenium-based photorelease antimicrobial therapy

ChemistryCondensed matterMedicineMicrobiologyPharmacy

By DIPC

Antimicrobial resistance is a complex problem that contributes to health and economic losses worldwide. Resistance to antimicrobial therapies reduces the effectiveness of current drugs, leading to increased morbidity, mortality, and health care expenditure. Because globalization increases the vulnerability of any country to diseases occurring in other countries, resistance presents a major threat to global public […]

The #microMOOCSEM initiative: Twitter as a tool for teaching and communicating science

The #microMOOCSEM initiative: Twitter as a tool for teaching and communicating science

EducationMicrobiology

By Ignacio López-Goñi

An innovative group of 30 international education professionals taught the first online microbiology course using Twitter, #microMOOCSEM, complete with lectures, videos, news, and more, with some classes reaching over 260,000 impressions and 3,700 retweets. Currently, most students are users of social networks like YouTube, Facebook or Twitter and have incorporated them, often unconsciously as powerful […]

Rabid aggression

Rabid aggression

BiologyMedicineMicrobiologyNeurobiology

By José Ramón Alonso

Rabies is a fatal viral disease largely transmitted to humans by infected animals—predominantly from domestic dogs. The contagion is usually through the saliva from rabid animals. The disease is entirely preventable through prompt administration of post-exposure prophylaxis to bite victims and can be controlled through widely applied vaccination of domestic dogs. Yet, rabies is still […]

Identified an immune cellular link between the gut microbiota and the brain

Identified an immune cellular link between the gut microbiota and the brain

MicrobiologyNeurobiology

By Rosa García-Verdugo

For a while, new evidence has been accumulating linking the gut microbiota to brain function. A new paper published recently in Cell Reports, shows that the intermediary is a type of white blood cell, evidencing as well the relationship between the brain and the immune system. While the crosstalk between the peripheral immune system and […]