Acute myeloid leukemia (AML) is a major hematopoietic malignancy characterized by the uncontrolled expansion of the immature myeloid cells . The 5-year survival rates of young patients are 40–50% and less than 15% for patients aged over 60 . For this reason, a great effort has been made to decipher the molecular events underlying AML […]
Authors: Eva-Maria Geigl, Directrice de recherche CNRS, co-responsable de l’équipe Épigénome et paléogénome de l’Institut Jacques Monod, Université Paris Cité; Oğuzhan Parasayan, Chercheur post-doctoral, Institut Pasteur, and Thierry Grange, Directeur de Recherche CNRS, co-responsable d’équipe de recherche, Institut Jacques Monod, Université Paris Cité High-resolution analysis of the genomes of individuals buried in a 4,500-year-old collective […]
Author: Claire Hendershot, Broad Institute of MIT and Harvard Developing a new drug can take years of research and cost millions of dollars. Still, more than 90% of drug candidates fail in clinical trials, with even more that never make it to the clinical stage. Many drugs fail because they simply aren’t safe. Researchers at […]
Author: José R. Pineda got his Ph.D. from University of Barcelona in 2006. Since 2007 he has worked for Institut Curie and The French Alternative Energies and Atomic Energy Commission. Currently he is a researcher of the UPV/EHU. He investigates the role of stem cells in physiologic and pathologic conditions. There is strong evidence that […]
Adopting a more sustainable energy portfolio is imperative to address and alleviate the impacts of climate change. A key process is energy harvesting versus energy “production”. In this vein, a potentially viable approach involves the conversion of dissipated heat into electrical energy via the use of thermoelectricity. This method has the potential to contribute significantly […]
The evolution of the human being has a complex form in which some branches bifurcate and form two different species and some different branches come together again and form individuals with a certain degree of hybridization. The only hominin remaining today is Homo sapiens and the last to disappear was Homo neanderthalensis. Neanderthals, our closest […]
You can think of our atmosphere as a big chemistry set, a global churn of gaseous molecules and particles that constantly bounce off and change each other in complicated ways. While the particles are very small, often less than 1% of the thickness of human hair, they have outsized impacts. For example, particles are the […]
Memory is so much more than a storage unit in our minds. The people involved in memories influence what we recall, and, as our study shows, the connections we make between memories. Our memory helps us learn from experiences and develop new knowledge by integrating and updating information. This process goes beyond recalling individual events […]
As the world’s largest unfrozen freshwater resource, groundwater is crucial for life on Earth. Now, a team of researchers has investigated how global warming is affecting groundwater temperatures and what that means for humanity and the environment . The study indicates that by 2100, more than 75 million people are likely to be living in […]
Our DNA is a puzzle resulting from millions of years of evolution. An ancient part of it is composed of the genetic material of viruses that integrated in our genome and became part of “us.” Though it may seem strange, about 7% of our genomes are comprised by these old viral sequences. What’s more, recent […]