Category archives: Biomedicine

Targeting melanoma: dynamic rewiring of signaling pathways contributes to drug resistance in tumors

Targeting melanoma: dynamic rewiring of signaling pathways contributes to drug resistance in tumors

BiomedicineGeneticsMedicine

By Miguel Vizoso

The scientific community, in their different fields and specialties, has made tremendous progress regarding human health and how we deal with all the maladies affecting mankind. Particularly in cancer, the Pulitzer Prize-winning book entitled “The Emperor of All Maladies” summarizes in a marvelous way this notion. However, I am convinced that our struggle against cancer […]

Alzheimer’s disease: type 3 diabetes?

Alzheimer’s disease: type 3 diabetes?

BiomedicineHealthMedicine

By Jaime de Juan Sanz

Increasing numbers of people are developing diabetes in our society and current predictions estimate that nowadays this disease affects about 9% of the whole population. As a consequence, health care systems in industrialized countries have developed many types of clinical interventions that prevent and treat classic complications of this disease and improve the lifetime and […]

The brain has a direct connection to the lymphatic system

The brain has a direct connection to the lymphatic system

BiomedicineNeurobiologyNeuroscience

By José Ramón Alonso

The lymphatic system performs important immune functions, and runs parallel to the blood circulatory system to provide a secondary circulation that transports excess interstitial fluid, proteins and metabolic waste products from the systemic tissues back into the blood. For centuries, it was thought that the central nervous system lacks a lymphatic drainage system and the […]

Exosomes in cancer: corrupted messages that  transmit the metastatic impulse

Exosomes in cancer: corrupted messages that transmit the metastatic impulse

BiologyBiomedicine

By F. Javier Carmona

Just as people constantly exchange messages via email, cells communicate with each other and their microenvironment by sending and receiving packages of information; and as we react in one way or another depending on the news we get, cells respond to the “message” by changing the expression of their genes. Following the analogy, in a […]

Cell therapy as a cure for chronic pain

Cell therapy as a cure for chronic pain

BiomedicineMolecular biologyNeurobiology

By Sergio Laínez

The way we approach pain therapies doesn’t differ from the ones taken for other diseases. The aim is to look for molecular targets, which can be suitable for chemical intervention thoroughly assessing both efficacy and safety profiles for the drug, issues that are addressed throughout various stages of clinical trials. In the specific case of […]

The Hepatitis C dilemma

The Hepatitis C dilemma

BiomedicinePharmacy

By Sergio Laínez

Most people in Spain have heard about the ongoing bitter polemic between the Victims of Hepatitis C Platform and the Spanish government with regard to the access to a new medication called Sovaldi approved by the Spanish government last 1st October. The main reason for such clash between them is simple: the asking price for […]

Dog’s DNA methylome uncovers hints on human cancer metastasis

Dog’s DNA methylome uncovers hints on human cancer metastasis

BiochemistryBiomedicineGenetics

By F. Javier Carmona

Tracking back human civilization there are evidences of dog domestication as far as 10,000 years ago. During this time, the ancient wolves’ genome evolved to give rise to the domestic dog that gradually adapted to human habitat as many organic functions were selected in detriment of others. Dogs have similar circadian rhythms, have adapted to […]