Category archives: Chemistry

Molecular recognition is a critical process for many biological functions and consists in non-covalent binding of different molecules, such as protein-protein, antigen-antibody and many others. The host-guest molecules involved often show a shape complementarity, and one of the leading specification for molecular recognition is that the interaction must be selective, i.e. the host should strongly […]

A catalyst is a substance that increases the rate of a chemical reaction without itself undergoing any permanent chemical change. As the catalyst itself takes part in the reaction it may undergo a physical change. Hence, if catalysts take the form of nanoparticles, any physical feature of the nanoparticle interacting with the reacting molecules may […]

Some heteropolymers can be designed to spontaneously self-assemble in complex pre-determined knotted structures. In the past, we referred to such designable heteropolymers as “bionic proteins”. Here we present an extensive study on self-knotting bionic proteins. As our everyday experience with ropes teaches us, knots form spontaneously in polymer chains of sufficient length and flexibility have […]

A quantum dot is a nanometric crystalline structure of semiconductor materials. In a quatum dot electrons are confined in a region of space, thus creating a well defined structure of energy levels that depends very much on the size and shape of the quantum dot. This structure resembles that of atoms, that is why sometimes […]

In the transition from a petrol-based society to a one based on bio-renewable resources, the replacement of aromatic chemicals is one of the most challenging issues. Nowadays, around 40% of the bulk chemicals belong to the aromatic category, and a myriad of products are derived from benzene, toluene and xylene. Aromatic molecules are present in […]

When nanoparticles (NPs) get in contact with biological fluids such as blood, proteins present in it will adsorb on the surface of those NPs forming what is known as the protein corona . It is a dynamic process in equilibrium with the surrounding proteins and it may lead to drastic changes in the NPs. The […]

Endohedral fullerenes, also called endofullerenes, are fullerenes that have additional atoms, ions, or clusters enclosed within their inner spheres. The first lanthanum C60 complex was synthesized in 1985 and called La@C60. The @ (at sign) in the name reflects the notion of a small molecule trapped inside a shell. The chemistry of endohedral fullerenes is […]

Common glass, used in windows or bottles, for example, is made by heating a mixture of calcium oxide (lime), sodium carbonate (soda), and silicon (IV) oxide (sand), resulting in a calcium silicate. This silicate is not a crystal but a solid in which atoms are positioned at random and have no long-range ordered pattern. These […]

It is time to round off this trilogy of articles about the importance of basic science nowadays. But first, how does science improve? A research team selects a topic, creates its hypothesis and workflow and, perhaps, tries to publish an article with the findings. This article is read by a new research team, who will […]

Author: Francisco J. Blanco is an Ikerbasque Research Professor at CIC bioGUNE Molecular interactions in cell membranes, particularly lipid-protein interactions in their hydrophobic core, are difficult to analyse and remain poorly characterised despite high relevance in physiological and pathological processes. Structural rearrangements in membranes and embedded proteins, and the way molecular interactions contribute to their […]