Category archives: Chemistry

Lead-oriented synthesis: a new concept to aid drug-discovery process

Lead-oriented synthesis: a new concept to aid drug-discovery process

ChemistryMedicinePharmacy

By Pablo Ortiz

The discovery and development of new drugs is a long and expensive process, and despite of it, essential to face present and new diseases. For small molecules, which account for the majority of the marketed drugs, the discovery process generally involves finding a starting point termed hit or lead compound. These molecules have biological activity […]

Living beings: systems all the way back to their chemical origins

Living beings: systems all the way back to their chemical origins

BiochemistryBiologyChemistryEvolution

By Invited Researcher

Author: Kepa Ruiz-Mirazo, Permanent Researcher, University of the Basque Country (UPV-EHU) The effort of mapping ignorance in biology is especially frustrating –or, if the mood and attitude of the scientist afford it, especially motivating– because solid, definite answers remain minimal compared to the amount of open issues and uncertainties that new discoveries in this field […]

Carnivorous plants inspire novel liquid repellent surfaces

Carnivorous plants inspire novel liquid repellent surfaces

ChemistryMaterialsPhysics

By Mireia Altimira

Natural non-wetting structures, particularly lotus leaves (Fig. 1a), have inspired the development of synthetic liquid-repellent surfaces. These surfaces rely on the formation of a stable air–liquid interface, but present limited repellency to oils with high contact angle hysteresis, failure under pressure and inability to self-heal. The paper by Wong et al. presents a novel approach […]