Recently, the journal Science showed in its cover an amazing image of a close up into the fly brain. This is the result of the combined effort of two research groups working on imaging. The first one (Boyden’s) had developed a way to increase the size of preserved samples, like a brain slice, up to […]
When nanoparticles (NPs) get in contact with biological fluids such as blood, proteins present in it will adsorb on the surface of those NPs forming what is known as the protein corona . It is a dynamic process in equilibrium with the surrounding proteins and it may lead to drastic changes in the NPs. The […]
Author: Leyre Urigüen is a researcher at the Department of Pharmacology, University of the Basque Country UPV/EHU and Centro de Investigación Biomédica en Red de Salud Mental CIBERSAM Cannabis, also called marijuana, is a drug that comes from the plant Cannabis sativa (hemp plant). The plant contains more than 400 different chemicals, of which approximately […]
Author: Francisco J. Blanco is an Ikerbasque Research Professor at CIC bioGUNE Molecular interactions in cell membranes, particularly lipid-protein interactions in their hydrophobic core, are difficult to analyse and remain poorly characterised despite high relevance in physiological and pathological processes. Structural rearrangements in membranes and embedded proteins, and the way molecular interactions contribute to their […]
Author: Iker Badiola is an assistant professor in the Department of Cell Biology and Histology, Faculty of Medicine and Nursery, University of Basque Country (UPV/EHU). Colorectal cancer is the third most frequently occurring cancer and a common cause of cancer-related death worldwide. The origin of colorectal cancer is usually a malignant polyp developed in the […]
The haploid human genome contains approximately 3,000,000,000 base pairs of DNA packaged into 23 chromosomes. Most cells in the body, except for eggs and sperm, are diploid, with 23 pairs of chromosomes. That makes a total of 6,000,000,000 base pairs of DNA per cell that, if they were to be put in a straight line […]
Estrogens are steroid hormones affecting several organs including mammary glands. More precisely, these glands exert their action by means of estrogens through the e strogen receptor (ER), a transcription factor belonging to the family of nuclear receptors. So far, two types of ERs have been identified: alpha and beta. ER-beta is expressed in all mammary […]
During the Cold War the competition between both sides, Russia and the United States of America, caused a quick development of military and spacial technology: while the Soviet Union was the first country responsible for an orbital launch (Sputnik 1), the first nation to ever send a man to space and pioneered spacewalks, the U […]
Like the river of Heraclitus, our bones are constantly changing. Although it may look tough and immutable , the bone is a very dynamic tissue that is constantly formed and destroyed, having different appearances during each of the stages of life. Bone destruction or reabsorption is mediated by a particular cellular type known as the […]
The mineralocorticoid receptor (MR) is an atypical nuclear receptor. In principle, it may seem a mere receptor with a specific ligand and an evident role: it is capable of detecting mineralocorticoids (like aldosterone), exerting an essential function controlling sodium and water reabsorption in the kidneys. In fact, knockout mice lacking MR die shortly after being […]