Category archives: Neurobiology

Chronic wasting disease in Europe

Chronic wasting disease in Europe

HealthMedicineNeurobiology

By José Ramón Alonso

Prion diseases are a group of severe conditions that affect the nervous system of many animals, including humans. Although their causes were highly controversial, there is a widespread agreement nowadays that they are originated and transmitted by prions, infectious agents with a normal and an abnormal structure. The abnormal prion protein infects the host animal […]

Can a mouse stammer?

Can a mouse stammer?

BiologyGeneticsNeurobiology

By José Ramón Alonso

Stammering, stuttering or alalia literalis is a speech disorder characterized by involuntary repetition and prolongations of sounds, syllables, words or phrases and involuntary silent pauses or blocks where the affected person is unable to produce sounds. Around 1-in-20 children aged 2 to 5 years old will stammer at some moment, but most grow out of […]

Neurogenesis and Zika virus

Neurogenesis and Zika virus

HealthNeurobiology

By José Ramón Alonso

Neurogenesis is the process by which neurons are generated from neural stem cells and progenitor cells. It is a crucial part of neural development and is most active during pre-natal life, being responsible for populating the growing brain with neurons. Zika virus is an emerging mosquito-borne and sexually-transmitted flavivirus that was first identified in Uganda […]

A Renaissance brain

A Renaissance brain

HistoryNeurobiology

By José Viosca

He was a man of insatiable curiosity and a hallmark of modern multidisciplinarity. Yet he was born on an April day six centuries ago. He never attended university, and still he authored masterpieces in the history of art and cultivated a broad range of interests and skills. Distant domains such as painting, sculpture, technology and […]

Breaking the barrier

Breaking the barrier

Neurobiology

By José Ramón Alonso

The blood-brain barrier is one of the defenses of the central nervous system. It is made of a thin layer of endothelial cells closely fitted together by tight junctions, being a mandatory pass between the blood and the neural cells. Thus, this barrier, considered the last great biochemical barricade in the organism, separates the blood […]

Fight suicide!

Fight suicide!

HealthNeurobiologyPharmacy

By José Ramón Alonso

Suicide is one of the worst health and social problems in the modern world. Hundreds of millions of persons experience suicidal thoughts every year and between 10 and 20 millions went on to attempt suicide. In Spain, although the average risk is lower than in Northern countries, almost 4.000 persons die every year by their […]

Human-mouse chimeras

Human-mouse chimeras

Neurobiology

By José Ramón Alonso

Chimera was a monster from the Greek mythology, a hybrid creature usually depicted as a lion, with the head of a goat arising from its back and a tail ending in a snake. In biology, the term «chimera» is used for a single organism with genetically distinct cells from two different zygotes, also a hybrid […]

What if Alzheimer’s disease was caused by fungi?

What if Alzheimer’s disease was caused by fungi?

HealthMedicineNeurobiologyNeuroscience

By Ignacio Amigo

More than a hundred years have passed since the German physicist Alois Alzheimer associated the traits of dementia of one of her patients with morphological changes in her brain after her death. While we know a great deal about what today is known as Alzheimer’s disease, we still need to answer two fundamental questions: what […]