Article archives

Lead-oriented synthesis: a new concept to aid drug-discovery process

Lead-oriented synthesis: a new concept to aid drug-discovery process

ChemistryMedicinePharmacy

By Pablo Ortiz

The discovery and development of new drugs is a long and expensive process, and despite of it, essential to face present and new diseases. For small molecules, which account for the majority of the marketed drugs, the discovery process generally involves finding a starting point termed hit or lead compound. These molecules have biological activity […]

MI weekly selection #81

MI weekly selection #81

Humanities & Social SciencesScienceTechnologyWeekly Selection

By César Tomé

Looks like a mouse but is genetically related to elephants A tiny, long-nosed creature found in western Africa looks like a mouse, but is genetically closer to an elephant, according research published in the Journal of Mammalogy. Biologists who discovered the new species of elephant shrew call it Macroscelides micus. It lives in an ancient […]

Grasshopper mouse mighty powers against evil bark scorpion: a molecular tale

Grasshopper mouse mighty powers against evil bark scorpion: a molecular tale

BiochemistryBiomedicineMolecular biologyNeurobiology

By Sergio Laínez

Natural selection has been sculpturing living organisms for millions of years, enabling them to get adapted to an ever-changing environment. Gradually, certain traits are selected over others based on the advantage they confer to the population. Natural selection is not a random process and it relies on genetic variation. Random mutations serve as the substrate […]

MI weekly selection #80

MI weekly selection #80

Humanities & Social SciencesScienceTechnologyWeekly Selection

By César Tomé

Hidden portrait lies behind Picasso’s “Blue Room” Scientists using infrared technology have revealed a portrait of a bearded man resting his head on his hand underneath Pablo Picasso’s 1901 painting “The Blue Room.” Picasso often reused canvasses because he couldn’t afford new ones, according to art experts. Two years ago, another portrait was found underneath […]

Stuck like a gecko

Stuck like a gecko

BiologyMaterials

By Silvia Román

We all know the story of that Swiss engineer who came up with the hoop-and-loop fastener system (also known under the brand name Velcro ) just by paying attention to the burdock burrs stuck in his clothes and his dog’s fur after a walk in the Alps. When he put these burrs under the microscope […]