Autism is a highly prevalent spectrum disorder of the neurodevelopment. It is characterized by impaired social interaction, alterations in verbal and non-verbal communication, and restricted and repetitive behaviors. Considering these main differences, it had been difficult to have good animal models since these interactions were initially defined for humans but scientists are nowadays developing different […]
Laboratory mice are one of the most valuable tools scientists rely on to understand how pathologies work. In order to find a cure for a disease, we need to have comprehensive knowledge of the physiological processes which are impaired. For instance, we can manipulate mice genetically to assess the effect of either the deletion, overexpression […]
If you feel stuck for words every once in a while, the most straightforward answer is that there is nothing wrong with you. Fifty years ago, Roger Brown and David McNeill at Harvard University showed that it is possible to trigger “a state in which one cannot quite recall a familiar word but can recall […]
Around 80% of the single nucleotide polymorphisms (SNPs) associated to many human diseases map to non-coding regions. Long non-coding RNAs (lncRNAs) represent a large portion of non-coding regions across the genome, however the link between the disease-associated SNPs on lncRNA expression or function, and the implications for disease, remain uncharacterized. Celiac disease is complex immune […]
Prion diseases are a group of severe conditions that affect the nervous system of many animals, including humans. Although their causes were highly controversial, there is a widespread agreement nowadays that they are originated and transmitted by prions, infectious agents with a normal and an abnormal structure. The abnormal prion protein infects the host animal […]
Humans are naturally social. Yet, the modern way of life in developed countries is greatly reducing the quality and quantity of social relationships despite the use of modern technologies that provide an illusory richness of interpersonal contacts. Many people in industrialized nations live far from their relatives, delay getting married, and more and more people […]
It is not only a piece of matter that moves but also a universe of meanings and contexts. For philosophers, the word Meaning is everything but trivial. In a crowded street, you may point the location of the closest train station by extending your arm at speed in the direction of someone else’s head – […]
Biology • Biomedicine • Health • Medicine
What are lysosomes doing inside your cells? When I was in High School my teacher used to say that lysosomes are only the trash bin of the cell. 20 years later we have discovered a dozen new functions that make this small organelle a core component of the cell. You may already know that the […]
Another busy day unfolds through dozens of medical visits, prescriptions, and auscultations. The next patient, a medication-resistant chronic back pain case, enters the office and asks the doctor whether acupuncture has something to do with placebos. The physician feels like the artful and evidence-based bedrocks of his medical praxis are called into a tug-of-war. A […]
Neurogenesis is the process by which neurons are generated from neural stem cells and progenitor cells. It is a crucial part of neural development and is most active during pre-natal life, being responsible for populating the growing brain with neurons. Zika virus is an emerging mosquito-borne and sexually-transmitted flavivirus that was first identified in Uganda […]