Around 80% of the single nucleotide polymorphisms (SNPs) associated to many human diseases map to non-coding regions. Long non-coding RNAs (lncRNAs) represent a large portion of non-coding regions across the genome, however the link between the disease-associated SNPs on lncRNA expression or function, and the implications for disease, remain uncharacterized. Celiac disease is complex immune […]
Prion diseases are a group of severe conditions that affect the nervous system of many animals, including humans. Although their causes were highly controversial, there is a widespread agreement nowadays that they are originated and transmitted by prions, infectious agents with a normal and an abnormal structure. The abnormal prion protein infects the host animal […]
Humans are naturally social. Yet, the modern way of life in developed countries is greatly reducing the quality and quantity of social relationships despite the use of modern technologies that provide an illusory richness of interpersonal contacts. Many people in industrialized nations live far from their relatives, delay getting married, and more and more people […]
It is not only a piece of matter that moves but also a universe of meanings and contexts. For philosophers, the word Meaning is everything but trivial. In a crowded street, you may point the location of the closest train station by extending your arm at speed in the direction of someone else’s head – […]
Biology • Biomedicine • Health • Medicine
What are lysosomes doing inside your cells? When I was in High School my teacher used to say that lysosomes are only the trash bin of the cell. 20 years later we have discovered a dozen new functions that make this small organelle a core component of the cell. You may already know that the […]
Another busy day unfolds through dozens of medical visits, prescriptions, and auscultations. The next patient, a medication-resistant chronic back pain case, enters the office and asks the doctor whether acupuncture has something to do with placebos. The physician feels like the artful and evidence-based bedrocks of his medical praxis are called into a tug-of-war. A […]
Neurogenesis is the process by which neurons are generated from neural stem cells and progenitor cells. It is a crucial part of neural development and is most active during pre-natal life, being responsible for populating the growing brain with neurons. Zika virus is an emerging mosquito-borne and sexually-transmitted flavivirus that was first identified in Uganda […]
The finding that modern humans coexisted and mated with Neanderthals 50000 years ago was a breakthrough when it was announced in 2010. As a result of interbreeding, the genomes of all modern Eurasians contain a small Neanderthal DNA load that has been calculated to be between 1.5% and 4%. Most Africans, however, lack this DNA […]
Ethics • Health • Psychology
Almost desperate, Rodrigo – the name is fictitious- visits his doctor seeking a solution for a chronic back pain he has been suffering for the last three years. After trying five different medications, none of them with effect, he receives an unexpected suggestion from his uncle, who encourages him to try acupuncture. He himself has […]
Suicide is one of the worst health and social problems in the modern world. Hundreds of millions of persons experience suicidal thoughts every year and between 10 and 20 millions went on to attempt suicide. In Spain, although the average risk is lower than in Northern countries, almost 4.000 persons die every year by their […]