A long time ago, Aaron Burr Jr. (1756 –1836), the Vice-President of the United States under Thomas Jefferson said something that is still applicable today: “The rule of my life is to make business a pleasure, and pleasure my business”. This is because current society demands the same things as Burr society: good food, free […]
Cell signalling is the mechanism by which cells communicate with each other and with their environment. Stimuli, which are generally chemical, are transmitted via a signalling cascade to effector molecules that orchestrate the appropriate response. Signalling pathways are not isolated but they rather form a complex network of biochemical reactions that regulate processes such as […]
There is a word everybody fears and that is because when you listen to it out loud, it could be too late. Even though we have likely coexisted with cancer since complex multicellular organisms evolved, to us human beings, it just seems the number of cases keeps growing every year. Sadly, that seems to be […]
When autumn arrives to temperate climate forests, deciduous trees lose their characteristic green tonalities and start showing a wide spectrum of new colours: yellow, brown, orange, red… Chlorophyll reabsorption takes place in the leaves and carotenoids, present in a lower concentration, are exposed. These pigments are produced in all photosynthetic organisms, fungi and non-photosynthetic bacteria […]
Biochemistry • Chemistry • Condensed matter • Molecular biology
Nanopore DNA sequencing was one the ten scientific breakthroughs of 2016 highlighted by Science magazine. In principle, graphene is the perfect pore material for DNA sequencing . Its monoatomic thickness of 0.35 nm is similar to the DNA base spacing and graphene nanopores can be fabricated with a diameter of only 1.0 nm, about the […]
Around 80% of the single nucleotide polymorphisms (SNPs) associated to many human diseases map to non-coding regions. Long non-coding RNAs (lncRNAs) represent a large portion of non-coding regions across the genome, however the link between the disease-associated SNPs on lncRNA expression or function, and the implications for disease, remain uncharacterized. Celiac disease is complex immune […]
Unveiling the three-dimensional structure of proteins is one of the most useful strategies for understanding the molecular and cellular basis of human pathologies. Since proteins accomplish myriad cellular functions, but they are formed by combinations of only 20 different pieces, the way those pieces are coordinated is critical, and the tiniest difference can change forever […]
A uthor: Kepa Ruiz-Mirazo, Permanent Researcher, University of the Basque Country (UPV-EHU) Although «cracking the origins-of-life puzzle», regardless of the reputation of the journalist who tells the news, is clearly not within the reach of science quite yet, the article published a few weeks ago by Sutherland and colleagues in the UK , does constitute […]
“In the beginning, there was simplicity” Richard Dawkins, “The selfish gene”, chapter 2 The question of how life began on Earth is as old as the human race and has occupied the thoughts and time of scientists and philosophers for centuries, often causing conflict throughout history. From a scientific point of view, the several possibilities […]
On 6 June, 1944 (also termed “the D-day”), the Allied army irrupted into the shores of western France in what was called the Invasion of Normandy, during the last stages of World War II. The operation began with hundreds of amphibian landing vehicles emerging from the sea and unloading their cargo – the Infantry divisions […]