One of the worst things that can happen to someone that loves talking as much as I do is losing my voice. What to most people is just a temporary inconvenience -or a relief depending on who you ask- for some is a real hindrance. Patients that suffer from a permanent impairment to their ability […]
It all began in 1891, when Dr. William B. Coley, a bone sarcoma surgeon at the Memorial Hospital in New York, injected streptococcal organisms into a patient with inoperable cancer. He thought that the infection he induced would have the side effect of shrinking the malignant tumor… and quite surprisingly he was right! The patient’s […]
The scientific community, in their different fields and specialties, has made tremendous progress regarding human health and how we deal with all the maladies affecting mankind. Particularly in cancer, the Pulitzer Prize-winning book entitled “The Emperor of All Maladies” summarizes in a marvelous way this notion. However, I am convinced that our struggle against cancer […]
Increasing numbers of people are developing diabetes in our society and current predictions estimate that nowadays this disease affects about 9% of the whole population. As a consequence, health care systems in industrialized countries have developed many types of clinical interventions that prevent and treat classic complications of this disease and improve the lifetime and […]
The lymphatic system performs important immune functions, and runs parallel to the blood circulatory system to provide a secondary circulation that transports excess interstitial fluid, proteins and metabolic waste products from the systemic tissues back into the blood. For centuries, it was thought that the central nervous system lacks a lymphatic drainage system and the […]
Just as people constantly exchange messages via email, cells communicate with each other and their microenvironment by sending and receiving packages of information; and as we react in one way or another depending on the news we get, cells respond to the “message” by changing the expression of their genes. Following the analogy, in a […]
The way we approach pain therapies doesn’t differ from the ones taken for other diseases. The aim is to look for molecular targets, which can be suitable for chemical intervention thoroughly assessing both efficacy and safety profiles for the drug, issues that are addressed throughout various stages of clinical trials. In the specific case of […]
Enantiomers are any two molecules that are mirror images of each other, in the same way that, within a same person, left and right hands are: both hands look exactly the same but indeed they are not, as they cannot be superimposed. This is very easily seen when we try to put the wrong glove […]
Last Friday I was, as is always the case listening to an enthusiastic talk given by one of the PhD students from my department. As part of her PhD work, she is trying to understand why periodontitis, an inflammatory disease where gums get swollen as a consequence of bacterial infection, is essentially painless. This is […]
Most people in Spain have heard about the ongoing bitter polemic between the Victims of Hepatitis C Platform and the Spanish government with regard to the access to a new medication called Sovaldi approved by the Spanish government last 1st October. The main reason for such clash between them is simple: the asking price for […]