Proteins are sophisticated machines that perform most of our cellular activities. Proteins are codified in the cellular DNA and synthesized as linear chains that need to get properly folded in a 3D structure to become functional. This state is named native structure. Several perturbations can challenge the native structure of the proteins converting them into […]
Diabetes is a metabolic disorder characterized by an inefficiency to respond to the glucose requirements of the body, a process largely regulated by the popular hormone known as insulin. Insulin is produced and secreted in a specific type of cells in the pancreas called β-cells, which are able to detect and respond to high glucose […]
Killing cancer cells is a key point to cure cancer. Many researchers are working on developing different therapies to do just that. The one I’m going to talk about today is a very promising one: Oncolytic Virotherapy. Just the name may scare you but it’s a very clever approach to treat some tumors lacking a […]
The advances in molecular biology and the so called post-genomic era, have improved significantly the fight against many human diseases, in some cases almost leading to their eradication. However, there are still regions of our planet were people suffer from infections and other causes of mortality which are easily avoided in the most developed countries […]
Nowadays there are quite a few compounds in clinical trials to assay their potential as breast cancer treatments. Some of them are the so called “PARP inhibitors”. These inhibitors work very well in tumours that have a deficiency in DNA repair because PARP proteins are involved in that process. However, a group of researchers working […]
A study published last year in The Lancet showed that a daily dose of aspirin reduces the risk of dying from several types of cancer. According to the authors’ data, long-term daily intake reduces the probability of dying from solid tumours by more than 30%. These results are consistent with known effects of aspirin blocking […]
