Over the last years, we have found out more and more about the vast amount of bacteria that live with and in us. These populations have been shown to play an important role in our health and are associated with diseases ranging from metabolic disorders such as obesity to autoimmune diseases or cancer. But do […]
Chemistry • Condensed matter • Medicine • Microbiology • Pharmacy
Antimicrobial resistance is a complex problem that contributes to health and economic losses worldwide. Resistance to antimicrobial therapies reduces the effectiveness of current drugs, leading to increased morbidity, mortality, and health care expenditure. Because globalization increases the vulnerability of any country to diseases occurring in other countries, resistance presents a major threat to global public […]
An innovative group of 30 international education professionals taught the first online microbiology course using Twitter, #microMOOCSEM, complete with lectures, videos, news, and more, with some classes reaching over 260,000 impressions and 3,700 retweets. Currently, most students are users of social networks like YouTube, Facebook or Twitter and have incorporated them, often unconsciously as powerful […]
Rabies is a fatal viral disease largely transmitted to humans by infected animals—predominantly from domestic dogs. The contagion is usually through the saliva from rabid animals. The disease is entirely preventable through prompt administration of post-exposure prophylaxis to bite victims and can be controlled through widely applied vaccination of domestic dogs. Yet, rabies is still […]
For a while, new evidence has been accumulating linking the gut microbiota to brain function. A new paper published recently in Cell Reports, shows that the intermediary is a type of white blood cell, evidencing as well the relationship between the brain and the immune system. While the crosstalk between the peripheral immune system and […]
It all began in 1891, when Dr. William B. Coley, a bone sarcoma surgeon at the Memorial Hospital in New York, injected streptococcal organisms into a patient with inoperable cancer. He thought that the infection he induced would have the side effect of shrinking the malignant tumor… and quite surprisingly he was right! The patient’s […]
Some pharmaceutical painkillers and analgesics like Noscapine, papaverine and tubocurarine or the most famous opioids codeine or morphine are Benzylisoquinoline derivatives. Few of them are used daily for thousands of people to relieve a variety of physical pains. However, due to their rather complex biosynthesis, they are still obtained by processing plant extracts (mainly from […]
Last Friday I was, as is always the case listening to an enthusiastic talk given by one of the PhD students from my department. As part of her PhD work, she is trying to understand why periodontitis, an inflammatory disease where gums get swollen as a consequence of bacterial infection, is essentially painless. This is […]
We are one of a kind because our genetic background says so. When our parents conceived us, one set of chromosomes from each of them merged to create a brand new diploid cell called zygote, which is already unique. Yet, such singularity doesn’t start with the zygote itself, but much earlier with our progenitors. The […]
There is a widespread concern about the increasing antibiotic resistance and the limited new drugs to treat infectious diseases, as discussed in a previous post . Consequently, the discovery of a new antibiotic active against a range of bacterial pathogens including Staphylococcus aureus has been greatly welcome, especially because no resistance to it has been […]