The study of nuclear receptors includes a great variety of approaches and techniques: from experiments with transgenic mice assessing their roles in the organism, to three-dimensional methods at the atomic level, in which the position of each amino acid and its function are examined. Dr. Estébanez’s research line focuses in the latter feature. T he […]
Our immune system comprises a great variety of cell types and each of these groups is specialized in separate and defined actions. Macrophages play an essential role within this defence system by enhancing the immune response. In particular, they are in charge of “swallowing” (technically speaking, fagocyting) waste products, foreign materials and microorganisms. In addition […]
The immune system is a complex network that recognises foreign substances in the body. When it detects an alien substance (antigen), it creates antibodies to attack and destroy it. This system protects vertebrates against viruses, bacteria, fungi and other parasites, and is the reason for the “rejection” after organ transplants. When we have cancer, our […]
W orld Health Organization (WHO) established the recognition of obesity as a disease in 1948, but it was not until the last decade of the 20th century that people began to gain awareness of overweight-derived health problems. A decade ago and based on worldwide data indicating that 40 % of global adult population were overweight […]
Collagen is the newest trendy nutrient. If we search for “collagen” in the web browser, we will find a wide variety of food supplements, cosmetic products and web pages where collagen beneficial effects are highlighted. Although collagen is a mere protein, its name is currently associated to the wellness circuit and, for this reason, it […]
Almost every one of our body cells bears in its nucleus about 2 meters of DNA containing the genes that shape our being. All that, roughly 20.000 protein-coding genes, regulatory and unknown-function sequences, tightly packed inside a structure that has a volume of only a few cubic micrometres. How this huge amount of material is […]
The immune system is composed of a considerable variety of cell types with different functions. One of the most important cells involved in the innate immunity are the macrophages . These cells have a wide spectrum of functions: from bacteria-killing function to wound healing properties. Classically the macrophages according to their functions have been classified […]
Aging is one of those topics mankind is always trying to understand, especially whether it can be reversed or stopped. With increasing age come not only alterations in appearance, but also associated changes like the degeneration of tissues such as muscles, bone and neural tissues or a higher predisposition for disease. In recent years, we […]
One of the priority objectives in autism research is to have a biological marker that allows early, rapid and reliable diagnosis. In the past year there have been several important studies that identified children with autism at ages as early as 6 or 12 months measuring volumetric changes in various regions of the brain or […]
Biochemistry • Chemistry • Condensed matter • Molecular biology
Nanopore DNA sequencing was one the ten scientific breakthroughs of 2016 highlighted by Science magazine. In principle, graphene is the perfect pore material for DNA sequencing . Its monoatomic thickness of 0.35 nm is similar to the DNA base spacing and graphene nanopores can be fabricated with a diameter of only 1.0 nm, about the […]