Author: Ramón Muñoz-Chápuli has been Professor of Animal Biology in the University of Málaga until his retirement. He has investigated for forty years in the fields of developmental biology and animal evolution. All the cells in our body require a supply of oxygen, although in some cases, they can temporarily rely on anaerobic metabolism. Under […]
Cutaneous Author: Marta Irigoyen is a postdoctoral researcher at CIC bioGUNE Cutaneous T-cell lymphoma (CTCL) is a rare type of cancer that begins in white blood cells called T cells (T lymphocytes). These cells normally help the body’s immune system to fight germs and pathogens. In cutaneous T-cell lymphoma, T cells acquire aberrant functions that […]
Hypoxia Author: Marta Irigoyen is a postdoctoral researcher at CIC bioGUNE Despite the fact that c ancer treatments have greatly improved during recent years, chemoresistance remains a major problem in eradicating cancer cells. Drug resistance involves not only many cell intrinsic mechanisms but also extrinsic induced chemoprotection by the tumor microenvironment . In fact, this […]
The recent COVID-19 pandemic has demonstrated the vulnerabilities of our society to infectious diseases and the limitations of the tools available for viruses detection. Polymerase chain reaction (PCR) and antigens tests have been useful to monitor and contain the extension of the last pandemic, however it demonstrated to have severe limitations. PCR is a highly […]
One of the biggest challenges of medical imaging technologies is actually resolving the structures of interest, be it a tumour, a lung or a blood vessel, without the “noise” from other bodily parts like skin or muscle. A new imaging technique allows for visualisation inside intact animals at higher resolution than ever before. A team […]
T-cell Author: Marta Irigoyen is a postdoctoral researcher at CIC bioGUNE T-ALL is an aggressive malignancy which results from the leukemic transformation of T-cell progenitors into tumor cells. It is widely accepted that complex interactions between T-ALL cells and their surrounding microenvironment contribute to disease and may regulate quiescence, survival and self-renewal of cancer cells […]
Biochemistry • Biomedicine • Health • Medicine • Neuroscience
Recent research has demonstrated that obesity impairs the mechanisms that allow our brains to realize when our stomachs are full and that these changes are maintained despite dieting, giving insights into why it is difficult for obese people to avoid excessive eating and why there is often a yo-yo effect after dieting. It has been […]
SARS-CoV-2 Author: José R. Pineda got his Ph.D. from University of Barcelona in 2006. Since 2007 he has worked for Institut Curie and The French Alternative Energies and Atomic Energy Commission. Currently he is a researcher of the UPV/EHU. He investigates the role of stem cells in physiologic and pathologic conditions. With 676.609.955 cases registered […]
Cancers are the second leading cause of death in the world, after cardiovascular diseases. Their seriousness lies in their diversity – some can be effectively treated with surgery, chemotherapy and radiotherapy, while others respond poorly or not at all. Improving the treatment of these diseases is therefore a major challenge. For several years, the development […]
Author: José R. Pineda got his Ph.D. from University of Barcelona in 2006. Since 2007 he has worked for Institut Curie and The French Alternative Energies and Atomic Energy Commission. Currently he is a researcher of the UPV/EHU. He investigates the role of stem cells in physiologic and pathologic conditions. Replicative senescence is a process […]